Kynureninase Antibody (589731)

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Kynureninase (KYNU) catalyzes the hydrolytic cleavage of the amino acids L-kynurenine and L-3-hydroxykynurenine to give either anthranilic acid or 3‑hydroxyanthranilic acid and alanine. KYNU and other “kynurenine pathway” enzymes degrade dietary tryptophan in the liver and are involved in the de novo biosynthesis of NAD⁺. KYNU and other pathway proteins in immune system cells, such as macrophages and microglia, catalyze inflammatory quinolinic acid (QA) production, which may cause neuronal damage in AIDS-related dementia complex, Alzheimer’s, stroke, epilepsy, and Huntington’s disease.  Human KYNU shares 83% and 85% amino acid identity with mouse and human KYNU, respectively.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Array MAB4887

• Kynureninase Antibodies
• Kynureninase ELISA Kits
• Kynureninase Lysate
• Kynureninase Protein
• Kynureninase Proteins and Enzyme