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Klotho Antibody [Janelia Fluor® 525]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Janelia Fluor 525

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP1-76511AF350
Alexa Fluor 405
NBP1-76511AF405
Alexa Fluor 488
NBP1-76511AF488
Alexa Fluor 532
NBP1-76511AF532
Alexa Fluor 594
NBP1-76511AF594
Alexa Fluor 647
NBP1-76511AF647
Alexa Fluor 700
NBP1-76511AF700
Alexa Fluor 750
NBP1-76511AF750
Biotin
NBP1-76511B
CoraFluor 1
NBP1-76511CL1
DyLight 350
NBP1-76511UV
DyLight 405
NBP1-76511V
DyLight 488
NBP1-76511G
DyLight 550
NBP1-76511R
DyLight 594
NBP1-76511DL594
DyLight 650
NBP1-76511C
DyLight 680
NBP1-76511FR
DyLight 755
NBP1-76511IR
FITC
NBP1-76511F
HRP
NBP1-76511H
Janelia Fluor 549
NBP1-76511JF549
Janelia Fluor 585
NBP1-76511JF585
Janelia Fluor 635
NBP1-76511JF635
Janelia Fluor 646
NBP1-76511JF646
Janelia Fluor 669
NBP1-76511JF669
PerCP
NBP1-76511PCP
Unconjugated
NBP1-76511
mFluor Violet 450 SE
NBP1-76511MFV450
mFluor Violet 500 SE
NBP1-76511MFV500
mFluor Violet 610 SE
NBP1-76511MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP1-76511
BSA Free
NBP1-76511
BSA Free
NBP1-76511-0.025mg
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Klotho Antibody [Janelia Fluor® 525] Summary

Immunogen
Antibody was raised against a peptide corresponding to 17 amino acids near the center of human Klotho. The immunogen is located within amino acids 410-460 of Klotho. Amino Acid Sequence: SGTTKRRDDAKYMYYLK
Specificity
Three isoforms of Klotho are known to exist. Human Klotho has 2 isoforms, including isoform 1 (1012aa, 116kD) and isoform 2 (549aa, 62kD). Mouse Klotho has 2 isoforms, including isoform 1 (1014aa, 116kD) and isoform 2 (550aa, 62kD). Rat Klotho has one isoform (1014aa, 117kD). NBP1-76511 can detect human, mouse and rat.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
KL
Purity
Peptide affinity purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Peptide affinity purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Klotho Antibody [Janelia Fluor® 525]

  • EC 3.2.1
  • EC 3.2.1.31
  • KL
  • Klotho

Background

The Klotho gene encodes a type-I membrane protein that is related to beta-glucosidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol KL