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Kir3.4 Antibody (8D2)

Images

 
Western Blot: Kir3.4 Antibody (8D2) [H00003762-M01-100ug] - Detection against Immunogen (36.63 KDa) .
Western Blot: Kir3.4 Antibody (8D2) [H00003762-M01-100ug] - KCNJ5 monoclonal antibody (M01), clone 8D2. Western Blot analysis of KCNJ5 expression in K-562.
ELISA: Kir3.4 Antibody (8D2) [H00003762-M01-100ug] - Detection limit for recombinant GST tagged KCNJ5 is 0.03 ng/ml as a capture antibody.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clone
8D2
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

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Kir3.4 Antibody (8D2) Summary

Immunogen
KCNJ5 (NP_000881.3, 321 a.a. ~ 419 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. SYMDTEVLWGHRFTPVLTLEKGFYEVDYNTFHDTYETNTPSCCAKELAEMKREGRLLQYLPSPPLLGGCAEAGLDAEAEQNEEDEPKGLGGSREARGSV
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
KCNJ5
Purity
Protein A or G purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • ELISA
  • Western Blot

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
In 1x PBS, pH 7.4
Preservative
No Preservative
Purity
Protein A or G purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Kir3.4 Antibody (8D2)

  • Cardiac inward rectifier
  • CIRKIR3.4
  • G protein-activated inward rectifier potassium channel 4
  • GIRK-4
  • GIRK4Kir3.4
  • Heart KATP channel
  • Inward rectifier K(+) channel Kir3.4
  • inward rectifier K+ channel KIR3.4
  • IRK-4
  • KATP-1
  • KATP1cardiac ATP-sensitive potassium channel
  • LQT13
  • Potassium channel, inwardly rectifying subfamily J member 5
  • potassium inwardly-rectifying channel, subfamily J, member 5

Background

G-protein regulated inward-rectifier potassium channels (GIRK) are part of a superfamily of inward-rectifier K+ channels. To date four GIRK subunits, designated GIRK1-4 (also designated Kir3.1-4), have been identified in mammals, and GIRK5 has been found in Xenopus oocytes. GIRK channels exist in vivo both as homotetramers and heterotetramers. GIRK channels are modulated by G-proteins; they are also modulated by phosphatidylinositol 4,5-bisphosphate, intracellular sodium, ethanol and mechanical stretch. GIRK1, 2 and 3 are highly abundant in brain. In general, neuronal GIRK channels are involved in the regulation of the excitability of neurons and may contribute to the resting potential.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Array H00003762-M01-100ug

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Bioinformatics

Gene Symbol KCNJ5
Entrez
OMIM
Uniprot