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Jagged 1 Antibody (188331) [PE/Cy7]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications Flow
Clone
188331
Clonality
Monoclonal
Host
Mouse
Conjugate
PE/Cy7

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB1277U-100UG
Alexa Fluor 405
FAB1277V-100UG
Alexa Fluor 488
FAB1277G-100UG
Alexa Fluor 532
FAB1277X
Alexa Fluor 594
FAB1277T-100UG
Alexa Fluor 647
FAB1277R-100UG
Alexa Fluor 700
FAB1277N-100UG
Alexa Fluor 750
FAB1277S-100UG
Allophycocyanin
FAB1277A
Allophycocyanin/Cy7
FAB1277APCCY7
Biotin
BAM1277
CoraFluor 1
FAB1277CL1
DyLight 350
FAB1277D
DyLight 405
FAB1277E
DyLight 488
FAB1277K
DyLight 550
FAB1277L
DyLight 594
FAB1277M
DyLight 650
FAB1277W
DyLight 680
FAB1277Y
DyLight 755
FAB1277Z
Fluorescein
FAB1277F
HRP
FAB1277H
Janelia Fluor 525
FAB1277JF525
Janelia Fluor 549
FAB1277I
Janelia Fluor 646
FAB1277J
Janelia Fluor 669
FAB1277JF669
PE
FAB1277P
PE/Atto594
FAB1277PEATT594
PE/Cy5.5
FAB1277PECY55
PerCP
FAB1277C
Unconjugated
MAB1277-100
mFluor Violet 450 SE
FAB1277MFV450
mFluor Violet 500 SE
FAB1277MFV500
mFluor Violet 610 SE
FAB1277MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB1277-100
Carrier Free
FAB1277F
Carrier Free
FAB1277A
Carrier Free
MAB1277-SP
Carrier Free
MAB1277-500
Carrier Free
MAB1277-100
Carrier Free
FAB1277V-100UG
Carrier Free
FAB1277U-100UG
Carrier Free
FAB1277T-100UG
Carrier Free
FAB1277S-100UG
Carrier Free
FAB1277R-100UG
Carrier Free
FAB1277N-100UG
Carrier Free
FAB1277G-100UG
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Jagged 1 Antibody (188331) [PE/Cy7] Summary

Immunogen
NS0-derived recombinant human Jagged 1
Ser32-Asp296
Accession # P78504
Specificity
Detects human, mouse, and rat Jagged 1. In direct ELISAs, no cross‑reactivity with recombinant human Jagged 2 is observed. Stains human Jagged 1 transfectants but not the parental cell line or human Jagged 2 transfectants in flow cytometry. 
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
JAG1
Purity
Protein A or G purified from hybridoma culture supernatant
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Applications/Dilutions

Dilutions
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Alternate Names for Jagged 1 Antibody (188331) [PE/Cy7]

  • AGS
  • AHDMGC104644
  • Alagille syndrome
  • AWS
  • CD339 antigen
  • CD339
  • HJ1
  • JAG1
  • Jagged 1
  • Jagged1
  • JAGL1
  • protein jagged-1

Background

The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is theligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations thatalter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play arole in hematopoiesis. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol JAG1