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Integrin alpha L/CD11a Antibody (CR38)

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Human peripheral blood monocytes were stained with Human Integrin alpha L/CD11a Monoclonal Antibody (Catalog # MAB35951, filled histogram) or isotype control antibody (Catalog # MAB003, open histogram), followed by Allophycocyanin-conjugated Anti-Mouse IgG F(ab')2 Secondary Antibody (Catalog # F0101B).
Human peripheral blood monocytes were stained with Human Integrin alpha L/CD11a Monoclonal Antibody (Catalog # MAB35951, filled histogram) or isotype control antibody (Catalog # MAB003, open histogram), followed by ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
CR38
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB35951U-100UG
Alexa Fluor 405
FAB35951V-100UG
Alexa Fluor 488
FAB35951G-100UG
Alexa Fluor 532
FAB35951X
Alexa Fluor 594
FAB35951T-100UG
Alexa Fluor 647
FAB35951R-100UG
Alexa Fluor 700
FAB35951N-100UG
Alexa Fluor 750
FAB35951S-100UG
Allophycocyanin/Cy7
FAB35951APCCY7
Biotin
FAB35951B
CoraFluor 1
FAB35951CL1
DyLight 350
FAB35951D
DyLight 405
FAB35951E
DyLight 488
FAB35951K
DyLight 550
FAB35951L
DyLight 594
FAB35951M
DyLight 650
FAB35951W
DyLight 680
FAB35951Y
DyLight 755
FAB35951Z
FITC
FAB35951F
HRP
FAB35951H
Janelia Fluor 525
FAB35951JF525
Janelia Fluor 549
FAB35951I
Janelia Fluor 635
FAB35951JF635
Janelia Fluor 646
FAB35951J
Janelia Fluor 669
FAB35951JF669
PE
FAB35951P
PE/Atto594
FAB35951PEATT594
PE/Cy5.5
FAB35951PECY55
PE/Cy7
FAB35951PECY7
mFluor Violet 450 SE
FAB35951MFV450
mFluor Violet 500 SE
FAB35951MFV500
mFluor Violet 610 SE
FAB35951MFV610
View Available Formulations
Catalog# & Formulation Size Price
Carrier Free
MAB35951-SP
Carrier Free
FAB35951V-100UG
Carrier Free
FAB35951U-100UG
Carrier Free
FAB35951T-100UG
Carrier Free
FAB35951S-100UG
Carrier Free
FAB35951R-100UG
Carrier Free
FAB35951N-100UG
Carrier Free
FAB35951G-100UG
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Integrin alpha L/CD11a Antibody (CR38) Summary

Immunogen
Fibronectin purified human monocytes
Specificity
Detects human Integrin alpha L/CD11a in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) Integrin alpha 1, alpha 2, alpha 3, alpha 4, alpha 5, alpha 6, alpha 8, alpha 9, alpha 10, alpha 11, alpha M, alpha V, alpha X, rhIntegrin beta 3, rhIntegrin alpha 6(x1)+ beta 4, alpha 7(x2)+ beta 1, alpha D+ beta 2, alpha E+ beta 7, recombinant mouse Integrin alpha 2b or alpha L is observed.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
ITGAL
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry 2.5 ug/10^6 cells
Publications
Read Publication using
MAB35951 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Sterile PBS to a final concentration of 0.5 mg/mL.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Integrin alpha L/CD11a Antibody (CR38)

  • CD11 antigen-like family member A
  • CD11a antigen
  • CD11a
  • CD11Aantigen CD11A (p180), lymphocyte function-associated antigen 1, alphapolypeptide
  • Integrin alpha L
  • integrin alpha-L
  • integrin gene promoter
  • integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen1; alpha polypeptide)
  • ITGAL
  • Leukocyte adhesion glycoprotein LFA-1 alpha chain
  • Leukocyte function-associated molecule 1 alpha chain
  • LFA-1 alpha
  • LFA-1
  • LFA1A
  • LFA-1A
  • Ly-15
  • Ly-21
  • lymphocyte function-associated antigen 1

Background

Integrin subunit alpha L/CD11a is a 180 kDa type I TM glycoprotein that interacts only with Integrin  beta 2/CD18 to form LFA-1, a leukocyte adhesion protein which binds endothelial cell ICAM. Human Integrin alpha L contains a 1064 aa extracellular domain (ECD), a 20 aa TM sequence and a 58 aa cytoplasmic domain. The ECD contains seven repeats that form a beta-propeller structure and one inserted vWA domain (I domain) containing a metal ion-dependent adhesion site (MIDAS). Human and mouse Integrin alpha L ECD share 74% aa identity. A second isoform has a 53 aa insert in the ECD.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Integrin alpha
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MAB35951
Integrin alpha L/CD11a Antibody (CR38)
Species: Hu
Applications: Flow, CyTOF-ready

Publications for Integrin alpha L/CD11a Antibody (MAB35951)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: Western Blot.


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Bioinformatics

Gene Symbol ITGAL