Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human IL-3 Ra/CD123 APC-conjugated Monoclonal Antibody (Catalog # FAB301A) and either (A) Mouse Anti-Human LILRB4/CD85k/ILT3 PE-conjugated ...read more
Mouse myeloma cell line NS0-derived recombinant human ILT3/CD85k Pro17-His257 Accession # ABM86208
Specificity
Detects human ILT3/CD85k in direct ELISAs and Western blots. In direct ELISAs, approximately 50% cross-reactivity with with recombinant human (rh) ILT5 is observed. No cross-reactivity with rhILT1, rhILT2, rhILT4, rhILT7, rhILT11, rhLIR-6 or rhLIR-8 is observed.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
LILRB4
Purity Statement
Protein A or G purified from hybridoma culture supernatant
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12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for ILT3/CD85k/LILRB4 Antibody (293623) [Phycoerythrin]
CD85 antigen-like family member K
CD85k antigen
CD85k
HM18
ILT3
ILT-3
ILT3CD85K
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains)
LILRB4
LIR5
LIR5LILRB5
LIR-5subfamily B, member 4
member 4
Background
Immunoglobulin-Like Transcript 3 (ILT3), also known as Leukocyte Immunoglobulin-Like Receptor subfamily B member 4 (LILRB4) and Leukocyte Immunoglobulin-like Receptor 5 (LIR-5), is a type I membrane protein that functions as a receptor for class I MHC antigens. It contains cytoplasmic ITIM motifs and is involved in the down-regulation of immune responses.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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