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IL1RAPL2 Antibody (320017) [Unconjugated]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB
Clone
320017
Clonality
Monoclonal
Host
Rat
Conjugate
Unconjugated
Concentration
LYOPH

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IL1RAPL2 Antibody (320017) [Unconjugated] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse IL1RAPL2
Asn18-Ala358
Accession # Q9ERS6
Specificity
Detects mouse IL1RAPL2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 25% cross‑reactivity with recombinant human (rh) IL1RAPL2 is observed and no cross-reactivity with recombinant mouse (rm) IL-1 R1, rmIL-1 R2, rmIL-1 R4, rmIL-1 Rrp2, rmSIGIRR, rhIL-1 R3, rhIL-1 R4, rhIL-1 Rrp2, or rhIL1RAPL1 is observed.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
IL1RAPL2
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1 ug/mL

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for IL1RAPL2 Antibody (320017) [Unconjugated]

  • IL-1R10
  • IL-1R-9
  • IL1R9IL-1 receptor accessory protein-like 2
  • IL-1R9IL-1RAPL-2
  • IL1RAPL2
  • IL-1RAPL2
  • IL-1-RAPL-2
  • IL1RAPL-2IL1RAPL-2-related protein
  • interleukin 1 receptor 9
  • interleukin 1 receptor accessory protein-like 2
  • Three immunoglobulin domain-containing IL-1 receptor-related 1
  • TIGIRR-1
  • TIGIRR-1Interleukin-1 receptor 9
  • X-linked interleukin-1 receptor accessory protein-like 2

Background

Interleukin 1 receptor accessory protein-like 2 (IL1RAPL2), also known as TIGIRR-1 and IL-1 R9, is a member of the IL-1 RI-like family of the IL-1 R/Toll-like receptor superfamily. IL1RAPL2 is a type I transmembrane protein that contains three Ig-like domains in its extracellular region and one intracellular TIR domain. IL1RAPL2 is expressed in the central nervous system, and its deletion is associated with some forms of X-linked mental retardation. An alternately spliced variant lacks the transmembrane and cytoplasmic regions. Within their extracellular domains, mouse IL1RAPL2 shares 99% amino acid sequence identity with human IL1RAPL2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol IL1RAPL2
Uniprot