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IL18R1 Antibody (MM0380-8H22) [Allophycocyanin]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC, B/N
Clone
MM0380-8H22
Clonality
Monoclonal
Host
Mouse
Conjugate
Allophycocyanin

Order Details

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IL18R1 Antibody (MM0380-8H22) [Allophycocyanin] Summary

Immunogen
Human recombinant IL18R1 (extracellular domain)
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
IL18R1
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Block/Neutralize
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Alternate Names for IL18R1 Antibody (MM0380-8H22) [Allophycocyanin]

  • CD218 antigen-like family member A
  • CD218a antigen
  • CD218a
  • CDw218a
  • cytokine receptor
  • IL-18R1
  • IL-18R-1
  • IL1R-rp
  • IL1RRPIL1 receptor-related protein
  • IL-1RrpIL18RA
  • interleukin 18 receptor 1
  • interleukin-18 receptor 1

Background

IL-18 receptor is composed of an alpha and a beta subunit that combine to form a high affinity receptor for IL-18. IL-18 receptor alpha chain, also known as CDw218a, is a 75-80 kD type I transmembrane protein. It is expressed on NK cells, neutrophils, endothelial cells, and subsets of T and B cells. The expression of CDw218a on lymphocytes is upregulated after activation. The interaction of IL-18 and IL-18 receptor has been reported to be implicated in promotion of Th1 cytokine production and atherogenesis. The H44 antibody is specific for IL-18 receptor alpha chain and has been reported to block IL-18 binding to the receptor and to be useful for the identification of IL-18 receptor by flow cytometry and IHC.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol IL18R1