Novus Biologicals products are now on bio-techne.com

IL-26/AK155 Antibody [Biotin]

Images

 
There are currently no images for IL-26/AK155 Antibody (BAF1375).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Goat
Conjugate
Biotin
Concentration
LYOPH

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
View Available Formulations
Novus Biologicals is part of Bio-Techne

Shop this product on bio-techne.com

IL-26/AK155 Antibody [Biotin] Summary

Immunogen
E. coli-derived recombinant human IL-26 (R&D Systems, Catalog # 1375-IL)
Lys22-Gln171
Accession # Q9NPH9
Specificity
Detects human IL-26 in Western blots. In this format, less than 2% cross-reactivity with recombinant human IL‑10 is observed.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
IL26
Purity Statement
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 0.1 ug/mL
Readout System
Publications
Read Publication using
BAF1375 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for IL-26/AK155 Antibody [Biotin]

  • AK155
  • AK155IL-26interleukin-26
  • IL26
  • IL-26
  • interleukin 26
  • Protein AK155

Background

IL-26 was originally cloned from herpesvirus saimiri (HVS)-transformed T cells and named AK155 (1). It is a member of the IL-10 family of class II cytokines that signal via heterodimeric receptor complexes composed of two type I transmembrane receptor subunits (2). The human IL-26 gene has been mapped to chromosome 12q15. It encodes a 171 amino acid polypeptide with a 21 amino acid signal peptide. In addition to HVS-transformed T cells, IL-26 is also expressed in other virus transformed T cell lines, fresh peripheral mononuclear cells, activated NK cells and T cells. A mouse homologue of human IL-26 has not been identified. IL-26 binds with high-affinity to the heterodimeric complex consisting of the ligand-binding IL-20 R alpha and non ligand-binding IL-10 R beta (3). Activation of the receptor complex results in rapid phosphorylation of STAT1 and STAT3. Although the IL-26 receptor complex is highly specific for IL-26 and is not activated by other class II cytokines, the individual subunits of the IL-26 receptor complex are components in receptor complexes for other class II cytokines (1). IL-20 R alpha can form dimers with IL-20 R beta to function as signaling receptors for IL-19, IL-20, and IL-24. IL-10 R beta  can complex with IL-10 R alpha , IL-22 R, and IL-28 R alpha  to transduce signals for IL-10, IL-22, and the three novel IFNs (IL-28A, IL-28B and IL-29), respectively. The physiological functions of IL-26 remain to be determined. IL-26 was reported to be a homodimer in solution (1).

  1. Knappe. A. et al. (2000) J. Virology 74:3881.
  2. Renauld, J.-C. (2003) Nature Reviews Immunology 3:667.
  3. Sheikh, F. et al. (2004) J. Immunol. 172(4):2006.
  4. Unpublished data (2003) R&D Systems, Inc.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

782-IL/CF
Species: Hu
Applications: BA
DY417
Species: Mu
Applications: ELISA
MAB15041
Species: Hu
Applications: CyTOF-ready, IHC, ICFlow, WB
AF1709
Species: Mu
Applications: Block, CyTOF-ready, ELISA(Cap), ELISA(Det), ELISA(Sta), ICFlow, WB
1102-IL/CF
Species: Hu
Applications: BA
DY1335B
Species: Hu
Applications: ELISA
D1900
Species: Hu
Applications: ELISA
DY421
Species: Mu
Applications: ELISA
MAB874
Species: Hu
Applications: CyTOF-ready, Flow, Neut, WB
D1900
Species: Hu
Applications: ELISA
MAB11761
Species: Hu
Applications: IHC
M6000B
Species: Mu
Applications: ELISA
MAB1799
Species: Hu, Mu, Rt
Applications: ICC, IP, ICFlow, KO, WB
AF2894
Species: Hu, Mu
Applications: CyTOF-ready, ICFlow, Simple Western, WB
1965-IL
Species: Hu
Applications: BA
8498-BP
Species: Hu
Applications: BA

Publications for IL-26/AK155 Antibody (BAF1375)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: ELISA Development.


Filter By Application
ELISA Development
(1)
All Applications
Filter By Species
Human
(1)
All Species

Reviews for IL-26/AK155 Antibody (BAF1375) (0)

There are no reviews for IL-26/AK155 Antibody (BAF1375). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for IL-26/AK155 Antibody (BAF1375) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.
Read our latest blog and use the new citation tool on bio-techne.com

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our IL-26/AK155 Antibody [Biotin] and receive a gift card or discount.

Bioinformatics

Gene Symbol IL26
Uniprot