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IL-1 RI Antibody (129304) [DyLight 680]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB, Flow, CyTOF-ready
Clone
129304
Clonality
Monoclonal
Host
Rat
Conjugate
DyLight 680

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB7712U-100UG
Alexa Fluor 405
FAB7712V-100UG
Alexa Fluor 488
FAB7712G-100UG
Alexa Fluor 532
FAB7712X
Alexa Fluor 594
FAB7712T-100UG
Alexa Fluor 647
FAB7712R-100UG
Alexa Fluor 700
FAB7712N-100UG
Alexa Fluor 750
FAB7712S-100UG
Allophycocyanin
FAB7712A
Allophycocyanin/Cy7
FAB7712APCCY7
Biotin
FAB7712B
DyLight 350
FAB7712D
DyLight 405
FAB7712E
DyLight 488
FAB7712K
DyLight 550
FAB7712L
DyLight 594
FAB7712M
DyLight 650
FAB7712W
DyLight 755
FAB7712Z
Fluorescein
FAB7712F-100
Fluorescein
FAB7712F-025
HRP
FAB7712H
Janelia Fluor 525
FAB7712JF525
Janelia Fluor 549
FAB7712I
Janelia Fluor 646
FAB7712J
Janelia Fluor 669
FAB7712JF669
PE/Atto594
FAB7712PEATT594
PE/Cy5.5
FAB7712PECY55
PE/Cy7
FAB7712PECY7
PerCP
FAB7712C
Phycoerythrin
FAB7712P-025
Phycoerythrin
FAB7712P-100
Unconjugated
MAB7712
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB7712
Carrier Free
FAB7712F-100
Carrier Free
FAB7712P-100
Carrier Free
FAB7712F-025
Carrier Free
FAB7712P-025
Carrier Free
MAB7712
Carrier Free
MAB7712-SP
Carrier Free
FAB7712U-100UG
Carrier Free
FAB7712T-100UG
Carrier Free
FAB7712S-100UG
Carrier Free
FAB7712R-100UG
Carrier Free
FAB7712N-100UG
Carrier Free
FAB7712G-100UG
Carrier Free
FAB7712V-100UG
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IL-1 RI Antibody (129304) [DyLight 680] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse IL-1 RI
Leu20-Lys338
Accession # P13504
Specificity
Detects mouse IL-1 R1 in direct ELISAs and Western blots.
Isotype
IgG2b
Clonality
Monoclonal
Host
Rat
Gene
IL1R1
Purity
Protein A or G purified from hybridoma culture supernatant
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for IL-1 RI Antibody (129304) [DyLight 680]

  • CD121 antigen-like family member A
  • CD121a antigen
  • CD121a
  • IL-1 RI
  • IL1R
  • IL1R1
  • IL1RI
  • IL-1RI
  • IL1RT1
  • IL-1RT1
  • IL-1RT-1
  • Interleukin 1 Receptor 1
  • interleukin 1 receptor, type I
  • interleukin receptor 1
  • interleukin-1 receptor type 1
  • p80

Background

The Interleukin 1 receptor type I (IL-1R1) belongs to the IL-1 receptor family (1). IL-1R1 binds to IL-1 alpha, IL-1 beta, and interleukin-1 receptor antagonist protein (IL-1RA). IL-1RA regulates IL-1 ligand biological activity by a competitive interaction for IL-1R1. Upon IL-1 stimulation, adaptor molecule MyD88 is first recruited to the IL-1R1-IL1R accessory protein complex, followed by the recruitment of two serine-threonine kinases, IRAK4 and IRAK, and the adaptor protein TRAF6, resulting in activation of the NF-kB pathway (2-3). Stimulation of IL-1R1, leads to activation of the transcription factors NF-B, ATF, and AP-1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol IL1R1