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IL-1 RI Antibody (129304) [PE/Cy7]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow
Clone
129304
Clonality
Monoclonal
Host
Rat
Conjugate
PE/Cy7

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB7712U-100UG
Alexa Fluor 405
FAB7712V-100UG
Alexa Fluor 488
FAB7712G-100UG
Alexa Fluor 532
FAB7712X
Alexa Fluor 594
FAB7712T-100UG
Alexa Fluor 647
FAB7712R-100UG
Alexa Fluor 700
FAB7712N-100UG
Alexa Fluor 750
FAB7712S-100UG
Allophycocyanin
FAB7712A
Allophycocyanin/Cy7
FAB7712APCCY7
Biotin
FAB7712B
DyLight 350
FAB7712D
DyLight 405
FAB7712E
DyLight 488
FAB7712K
DyLight 550
FAB7712L
DyLight 594
FAB7712M
DyLight 650
FAB7712W
DyLight 680
FAB7712Y
DyLight 755
FAB7712Z
Fluorescein
FAB7712F-100
Fluorescein
FAB7712F-025
HRP
FAB7712H
Janelia Fluor 525
FAB7712JF525
Janelia Fluor 549
FAB7712I
Janelia Fluor 646
FAB7712J
Janelia Fluor 669
FAB7712JF669
PE/Atto594
FAB7712PEATT594
PE/Cy5.5
FAB7712PECY55
PerCP
FAB7712C
Phycoerythrin
FAB7712P-025
Phycoerythrin
FAB7712P-100
Unconjugated
MAB7712
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB7712
Carrier Free
FAB7712F-100
Carrier Free
FAB7712P-100
Carrier Free
FAB7712F-025
Carrier Free
FAB7712P-025
Carrier Free
MAB7712
Carrier Free
MAB7712-SP
Carrier Free
FAB7712U-100UG
Carrier Free
FAB7712T-100UG
Carrier Free
FAB7712S-100UG
Carrier Free
FAB7712R-100UG
Carrier Free
FAB7712N-100UG
Carrier Free
FAB7712G-100UG
Carrier Free
FAB7712V-100UG
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IL-1 RI Antibody (129304) [PE/Cy7] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse IL-1 RI
Leu20-Lys338
Accession # P13504
Specificity
Detects mouse IL-1 R1 in direct ELISAs and Western blots.
Isotype
IgG2b
Clonality
Monoclonal
Host
Rat
Gene
IL1R1
Purity
Protein A or G purified from hybridoma culture supernatant
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Applications/Dilutions

Dilutions
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Alternate Names for IL-1 RI Antibody (129304) [PE/Cy7]

  • CD121 antigen-like family member A
  • CD121a antigen
  • CD121a
  • IL-1 RI
  • IL1R
  • IL1R1
  • IL1RI
  • IL-1RI
  • IL1RT1
  • IL-1RT1
  • IL-1RT-1
  • Interleukin 1 Receptor 1
  • interleukin 1 receptor, type I
  • interleukin receptor 1
  • interleukin-1 receptor type 1
  • p80

Background

The Interleukin 1 receptor type I (IL-1R1) belongs to the IL-1 receptor family (1). IL-1R1 binds to IL-1 alpha, IL-1 beta, and interleukin-1 receptor antagonist protein (IL-1RA). IL-1RA regulates IL-1 ligand biological activity by a competitive interaction for IL-1R1. Upon IL-1 stimulation, adaptor molecule MyD88 is first recruited to the IL-1R1-IL1R accessory protein complex, followed by the recruitment of two serine-threonine kinases, IRAK4 and IRAK, and the adaptor protein TRAF6, resulting in activation of the NF-kB pathway (2-3). Stimulation of IL-1R1, leads to activation of the transcription factors NF-B, ATF, and AP-1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol IL1R1