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Human P-Selectin/CD62P Quantikine ELISA Kit

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Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
HRP

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Human P-Selectin/CD62P Quantikine ELISA Kit Summary

Background
The Quantikine® Human P-Selectin/CD62P Immunoassay is a 1.25 hour solid-phase ELISA designed to measure human P-Selectin in cell culture supernates, serum, and plasma. It contains recombinant human P-Selectin and antibodies raised against the recombinant factor. Results obtained using natural human P-Selectin showed linear curves that were parallel to the standard curves obtained... using the Quantikine® kit standards. These results indicate that this kit can be used to determine relative mass values for natural human P-Selectin.
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Specificity
Rrecombinant and natural human P-Selectin
Source
N/A
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using
DPSE00 in the following applications:

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human P-Selectin/CD62P Quantikine ELISA Kit

  • CD62P antigen
  • CD62P
  • FLJ45155
  • GMP140
  • GRMP
  • PADGEM
  • PADGEMantigen CD62)
  • PSEL
  • P-Selectin
  • selectin P (granule membrane protein 140kDa, antigen CD62)
  • SELP

Background

The Selectin family is comprised of three members, E-Selectin, L-Selectin, and P-Selectin. E-Selectin [endothelial leukocyte adhesion molecule-1 (ELAM-1), CD62E] is transiently expressed on vascular endothelial cells in response to IL-1 beta and TNF-alpha. The human and rat proteins share approximately 67% amino acid sequence identity. The mouse and rat proteins share approximately 78% amino acid sequence identity. L-Selectin (Leukocyte Selectin, LAM-1, LECAM-1, LECCAM-1, TQ1, Leu-8, MEL-14 antigen, DREG, lymph node homing receptor, CD62L) is expressed constitutively on a wide variety of leukocytes. Two forms of L-Selectin have been reported, apparently arising as a result of post-translational modifications. Human and mouse L-Selectin share 76% amino acid sequence identity. Human P-Selectin (GMP-140, LECAM-3, PADGEM, CD62P) is expressed by activated platelets and endothelial cells. The extracellular domains of human and mouse P-Selectin share approximately 73% amino acid sequence identity.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for P-Selectin/CD62P (DPSE00)(18)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: ELISA Capture.


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ELISA Capture
(1)
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Human
(17)
All Species
Showing Publications 1 - 10 of 18. Show All 18 Publications.
Publications using DPSE00 Applications Species
Guo, CY;Mo, R;Kim, H; Surface topography modulates initial platelet adhesion to titanium substrata Journal of oral biology and craniofacial research 2024-06-07 [PMID: 38962718] (Human) Human
Illési, Á;Fejes, Z;Pócsi, M;Debreceni, IB;Hodosi, K;Nagy, B;Kappelmayer, J;K?szegi, Z;Csanádi, Z;Szük, T; Technically Challenging Percutaneous Interventions of Chronic Total Occlusions Are Associated with Enhanced Platelet Activation Journal of clinical medicine 2023-10-29 [PMID: 37959293]
Z?bczyk, M;Kruk, A;Natorska, J;Undas, A; Low-grade endotoxemia in acute pulmonary embolism: Links with prothrombotic plasma fibrin clot phenotype Thrombosis research 2023-12-01 [PMID: 37949000] (Human) Human
Sommer, P;Schreinlechner, M;Noflatscher, M;Lener, D;Mair, F;Theurl, M;Kirchmair, R;Marschang, P; Increasing Soluble P-Selectin Levels Predict Higher Peripheral Atherosclerotic Plaque Progression Journal of clinical medicine 2023-10-10 [PMID: 37892568] (Human) Human
Chyrchel, B;Kruszelnicka, O;Wieczorek-Surdacka, E;Surdacki, A; Association of ADP-Induced Whole-Blood Platelet Aggregation with Serum Low-Density Lipoprotein Cholesterol in Patients with Coronary Artery Disease When Receiving Maintenance Ticagrelor-Based Dual Antiplatelet Therapy Journal of clinical medicine 2023-07-06 [PMID: 37445565] (Human) Human
Y Harada, A Sato, A Nishioka, S Ogusu, M Matsumoto, E Sueoka, A Kawaguchi, S Kimura, N Sueoka-Ara Usefulness of blood biomarkers for predicting venous thromboembolism in Japanese patients with cancer Oncology Letters, 2023-03-17;25(5):180. 2023-03-17 [PMID: 37033099] (Human) Human
D Mehic, J Machacek, T Schramm, L Buresch, A Kaider, B Eichelberg, H Haslacher, M Fillitz, B Dixer, T Flasch, T Anderle, A Rath, A Assinger, C Ay, I Pabinger, J Gebhart Platelet function and soluble P-selectin in patients with primary immune thrombocytopenia Thrombosis Research, 2023-01-16;223(0):102-110. 2023-01-16 [PMID: 36738663] (Human) Human
JO Williams, J Nash, C Whelan, BM Raven, AJ Davies, J Evans, L Watkeys, K Morris, PE James Early but reversible haemostatic changes in a-symptomatic females expressing COVID-19 antibodies Thrombosis Research, 2022-07-25;217(0):76-85. 2022-07-25 [PMID: 35908384] (Human) Human
T Metzner, DR Leitner, G Dimsity, F Gunzer, P Opriessnig, K Mellitzer, A Beck, H Sourij, T Stojakovic, H Deutschman, W März, U Landmesser, M Brodmann, G Reishofer, H Scharnagl, H Toplak, G Silbernage Short-Term Treatment with Alirocumab, Flow-Dependent Dilatation of the Brachial Artery and Use of Magnetic Resonance Diffusion Tensor Imaging to Evaluate Vascular Structure: An Exploratory Pilot Study Biomedicines, 2022-01-11;10(1):. 2022-01-11 [PMID: 35052831] (Human) Human
L Solhi, HS Sun, SH Daswani, S Shojania, CMK Springate, H Brumer Controlled sulfation of mixed-linkage glucan by Response Surface Methodology for the development of biologically applicable polysaccharides Carbohydrate polymers, 2021-06-01;269(0):118275. 2021-06-01 [PMID: 34294307] (Human) Human
Show All 18 Publications.

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