Human P-Selectin/CD62P DuoSet ELISA, 15 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

The Selectin family is comprised of three members, E-Selectin, L-Selectin, and P-Selectin. E-Selectin [endothelial leukocyte adhesion molecule-1 (ELAM-1), CD62E] is transiently expressed on vascular endothelial cells in response to IL-1 beta and TNF-alpha. The human and rat proteins share approximately 67% amino acid sequence identity. The mouse and rat proteins share approximately 78% amino acid sequence identity. L-Selectin (Leukocyte Selectin, LAM-1, LECAM-1, LECCAM-1, TQ1, Leu-8, MEL-14 antigen, DREG, lymph node homing receptor, CD62L) is expressed constitutively on a wide variety of leukocytes. Two forms of L-Selectin have been reported, apparently arising as a result of post-translational modifications. Human and mouse L-Selectin share 76% amino acid sequence identity. Human P-Selectin (GMP-140, LECAM-3, PADGEM, CD62P) is expressed by activated platelets and endothelial cells. The extracellular domains of human and mouse P-Selectin share approximately 73% amino acid sequence identity.

We have publications tested in 1 confirmed species: Human.

Showing Publications 1 - 10 of 20. Show All 20 Publications. Collapse Publications.

Publications using DY137	Applications	Species
Lengvenyte, A;Cognasse, F;Hamzeh-Cognasse, H;Sénèque, M;Strumila, R;Olié, E;Courtet, P; Baseline circulating biomarkers, their changes, and subsequent suicidal ideation and depression severity at 6 months: A prospective analysis in patients with mood disorders Psychoneuroendocrinology 2024-07-06 [PMID: 39003840] (Human)		Human
Lekva, T;Sundaram, AYF;Roland, MCP;Åsheim, J;Michelsen, AE;Norwitz, ER;Aukrust, P;Gilfillan, GD;Ueland, T; Platelet and mitochondrial RNA is decreased in plasma-derived extracellular vesicles in women with preeclampsia-an exploratory study BMC medicine 2023-11-23 [PMID: 37996819] (Human)		Human
Tang, Z;Xu, Y;Tan, Y;Shi, H;Jin, P;Li, Y;Teng, J;Liu, H;Pan, H;Hu, Q;Cheng, X;Ye, J;Su, Y;Sun, Y;Meng, J;Zhou, Z;Chi, H;Wang, X;Liu, J;Lu, Y;Liu, F;Dai, J;Yang, C;Chen, S;Liu, T; CD36 mediates SARS-CoV-2-envelope-protein-induced platelet activation and thrombosis Nature communications 2023-08-21 [PMID: 37604832] (Human)		Human
Reis-Goes, FS;Silva, NN;Gondim, TM;Figueiredo, RG;Evangelista, GAO;Marchioro, SB;Costa, RS;Torres, AJL;Meyer, RJ;Trindade, SC;Fortuna, V; Exploring dysregulated immune response genes and endothelial dysfunction biomarkers as predictors of severe COVID-19 International immunopharmacology 2023-07-05 [PMID: 37453154] (Human)		Human
L Song, X Zhao, R Chen, J Li, J Zhou, C Liu, P Zhou, Y Wang, Y Chen, H Zhao, H Yan Association of PCSK9 with inflammation and platelet activation markers and recurrent cardiovascular risks in STEMI patients undergoing primary PCI with or without diabetes Cardiovascular Diabetology, 2022-05-20;21(1):80. 2022-05-20 [PMID: 35596184] (Human)		Human
KN Lee, KH Park, YM Kim, I Cho, TE Kim Prediction of emergency cerclage outcomes in women with cervical insufficiency: The role of inflammatory, angiogenic, and extracellular matrix-related proteins in amniotic fluid PLoS ONE, 2022-05-10;17(5):e0268291. 2022-05-10 [PMID: 35536791] (Human)		Human
MH Schutte, R Kleemann, NM Nota, CM Wiepjes, JM Snabel, G T'Sjoen, A Thijs, M den Heijer The effect of transdermal gender-affirming hormone therapy on markers of inflammation and hemostasis PLoS ONE, 2022-03-15;17(3):e0261312. 2022-03-15 [PMID: 35290388] (Human)		Human
E Fragopoulo, C Argyrou, M Detopoulou, S Tsitsou, S Seremeti, M Yannakouli, S Antonopoul, G Kolovou, P Kalogeropo The effect of moderate wine consumption on cytokine secretion by peripheral blood mononuclear cells: A randomized clinical study in coronary heart disease patients Cytokine, 2021-07-08;146(0):155629. 2021-07-08 [PMID: 34247040] (Human)		Human
TN Chimponda, C Mushayi, DNM Osakunor, A Vengesai, E Enwono, S Amanfo, J Murray, C Tshuma, F Mutapi, T Mduluza Elevation of C-reactive protein, P-selectin and Resistin as potential inflammatory biomarkers of urogenital Schistosomiasis exposure in preschool children BMC Infect. Dis., 2019-12-19;19(1):1071. 2019-12-19 [PMID: 31856765] (Human)		Human
I Govorov, K Bremme, A Larsson, M Holmström, E Komlichenk, R Chaireti, M Mints Blood inflammatory and endothelial markers in women with von Willebrand disease PLoS ONE, 2019-01-10;14(1):e0210544. 2019-01-10 [PMID: 30629692] (Human)		Human
GJ Nieuwenhui, TAJ van den Be, SJL Bakker, MC van den He, MMRF Struys, T Lisman, RA Pol Preemptively and non-preemptively transplanted patients show a comparable hypercoagulable state prior to kidney transplantation compared to living kidney donors PLoS ONE, 2018-07-16;13(7):e0200537. 2018-07-16 [PMID: 30011293] (Human)		Human
Erdman L, D'Acremont V, Hayford K, Rajwans N, Kilowoko M, Kyungu E, Hongoa P, Alamo L, Streiner D, Genton B, Kain K Biomarkers of Host Response Predict Primary End-Point Radiological Pneumonia in Tanzanian Children with Clinical Pneumonia: A Prospective Cohort Study. PLoS ONE, 2015-09-14;10(9):e0137592. 2015-09-14 [PMID: 26366571] (Human)		Human
Highly invasive melanoma cells activate the vascular endothelium via an MMP-2/integrin alphavbeta5-induced secretion of VEGF-A. Am. J. Pathol., 2012-05-31;181(2):693-705. 2012-05-31 [PMID: 22659470] (Human)		Human
van Bladel ER, Roest M Up-regulation of platelet activation in hemophilia A. Haematologica, 2011-03-21;0(0):. 2011-03-21 [PMID: 21422116] (Human)		Human
Erdman LK, Dhabangi A, Musoke C, Conroy AL, Hawkes M, Higgins S, Rajwans N, Wolofsky KT, Streiner DL, Liles WC, Cserti-Gazdewich CM, Kain KC Combinations of Host Biomarkers Predict Mortality among Ugandan Children with Severe Malaria: A Retrospective Case-Control Study. PLoS ONE, 2011-02-25;6(2):e17440. 2011-02-25 [PMID: 21364762] (Human)		Human
de Mast Q, de Groot PG, van Heerde WL, Roestenberg M, van Velzen JF, Verbruggen B, Roest M, McCall M, Nieman AE, Westendorp J, Syafruddin D, Fijnheer R, van Dongen-Lases EC, Sauerwein RW, van der Ven AJ Thrombocytopenia in early malaria is associated with GP1b shedding in absence of systemic platelet activation and consumptive coagulopathy. Br. J. Haematol., 2010-10-19;151(5):495-503. 2010-10-19 [PMID: 20955404] (Human)		Human
Snoep JD, Roest M, Barendrecht AD High platelet reactivity is associated with myocardial infarction in premenopausal women: a population-based case-control study. J. Thromb. Haemost., 2010-01-30;8(5):906-13. 2010-01-30 [PMID: 20128867] (Human)		Human
Araujo Penna I, Canella PR, Vieira CS, Silva de Sa MF, dos Reis RM, Ferriani RA Cardiovascular risk factors are reduced with a low dose of acarbose in obese patients with polycystic ovary syndrome. Fertil. Steril., 2007-04-06;88(2):519-22. 2007-04-06 [PMID: 17418836] (Human)		Human
Huck V, Niemeyer A, Goerge T, Schnaeker EM, Ossig R, Rogge P, Schneider MF, Oberleithner H, Schneider SW Delay of acute intracellular pH recovery after acidosis decreases endothelial cell activation. J. Cell. Physiol., 2007-05-01;211(2):399-409. 2007-05-01 [PMID: 17167769] (Human)		Human
Di Nisio M, Niers TM, Reitsma PH, Buller HR Plasma cytokine and P-selectin levels in advanced malignancy: prognostic value and impact of low-molecular weight heparin administration. Cancer, 2005-11-15;104(10):2275-81. 2005-11-15 [PMID: 16216004] (Human)		Human
Show All 20 Publications. Collapse Publications.

Array DY137

• P-Selectin/CD62P Antibodies
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