Human L-Selectin/CD62L DuoSet ELISA, 15 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

The Selectin family is comprised of three members, E-Selectin, L-Selectin, and P-Selectin. E-Selectin [endothelial leukocyte adhesion molecule-1 (ELAM-1), CD62E] is transiently expressed on vascular endothelial cells in response to IL-1 beta and TNF-alpha. The human and rat proteins share approximately 67% amino acid sequence identity. The mouse and rat proteins share approximately 78% amino acid sequence identity. L-Selectin (Leukocyte Selectin, LAM-1, LECAM-1, LECCAM-1, TQ1, Leu-8, MEL-14 antigen, DREG, lymph node homing receptor, CD62L) is expressed constitutively on a wide variety of leukocytes. Two forms of L-Selectin have been reported, apparently arising as a result of post-translational modifications. Human and mouse L-Selectin share 76% amino acid sequence identity. Human P-Selectin (GMP-140, LECAM-3, PADGEM, CD62P) is expressed by activated platelets and endothelial cells. The extracellular domains of human and mouse P-Selectin share approximately 73% amino acid sequence identity.

We have publications tested in 2 confirmed species: Human, Chinese Hamster.

Showing Publications 1 - 7 of 7.

Publications using DY728	Applications	Species
J Segura, J Ireland, Z Zou, G Roth, J Buchwald, TJ Shen, E Fischer, S Moir, TW Chun, PD Sun HIV-1 release requires Nef-induced caspase activation PLoS ONE, 2023-02-13;18(2):e0281087. 2023-02-13 [PMID: 36780482] (Human)		Human
HK Drescher, A Schippers, S Rosenhain, F Gremse, L Bongiovann, A Bruin, S Eswaran, SU Gallage, D Pfister, M Szydlowska, M Heikenwald, S Weiskirche, N Wagner, C Trautwein, R Weiskirche, DC Kroy L-Selectin/CD62L is a Key Driver of Non-Alcoholic Steatohepatitis in Mice and Men Cells, 2020-04-29;9(5):. 2020-04-29 [PMID: 32365632] (Human)		Human
AA Arguinano, NC Ndiaye, C Masson, S Visvikis-S Pleiotropy of ABO gene: correlation of rs644234 with E-selectin and lipid levels Clin. Chem. Lab. Med., 2018-04-25;0(0):. 2018-04-25 [PMID: 29373315] (Human)		Human
M Spencer, N Max, J Ireland, Z Zou, R Wang, P Sun Over-expression of a human CD62L ecto-domain and a potential role of RNA pseudoknot structures in recombinant protein expression Protein Expr. Purif., 2017-08-24;140(0):65-73. 2017-08-24 [PMID: 28842197] (Chinese Hamster)		Chinese Hamster
AA Aldasoro A, S Dadé, M Stathopoul, M Derive, N Coumba Ndi, T Xie, C Masson, S Gibot, S Visvikis-S TREM-1 SNP rs2234246 regulates TREM-1 protein and mRNA levels and is associated with plasma levels of L-selectin PLoS ONE, 2017-08-03;12(8):e0182226. 2017-08-03 [PMID: 28771614] (Human)		Human
PL Chiang, HL Chen, CH Lu, PC Chen, MH Chen, IH Yang, NW Tsai, WC Lin White matter damage and systemic inflammation in Parkinson's disease BMC Neurosci, 2017-06-08;18(1):48. 2017-06-08 [PMID: 28595572] (Human)		Human
Chang , Elizabet, Eckert , Mark A, Ali , M Monsur, Riazifar , Hamidrez, Pone , Egest J, Liu , Linan, Zhao , Weian Facile supermolecular aptamer inhibitors of L-selectin. PLoS ONE, 2015-03-31;10(3):e0123034. 2015-03-31 [PMID: 25826688] (Human)		Human

Array DY728

• L-Selectin/CD62L Antibodies
• L-Selectin/CD62L Antibody Pairs
• L-Selectin/CD62L ELISA Kits
• L-Selectin/CD62L Lysate
• L-Selectin/CD62L Protein
• L-Selectin/CD62L Proteins and Enzymes
• L-Selectin/CD62L ELISAs