Human IFN-gamma DuoSet ELISA, 15 Plate

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
Biotin

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Catalog# & Formulation Size Price

Human IFN-gamma DuoSet ELISA, 15 Plate Summary

Source
N/A
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DY285B.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human IFN-gamma DuoSet ELISA, 15 Plate

  • IFG
  • IFI
  • IFNG
  • IFNgamma
  • IFN-gamma
  • Immune interferon
  • interferon gamma
  • interferon, gamma

Background

IFN-gamma (Interferon-gamma) is the prototype proinflammatory cytokine and is produced by a variety of immune cells under inflammatory conditions, notably by T cells and NK cells. It plays a key role in host defense by promoting the development and activation of Th1 cells, chemoattraction and activation of monocytes and macrophages, upregulation of antigen presentation molecules, and immunoglobulin class switching in B cells. It also exhibits antiviral, antiproliferative, and apoptotic effects. In addition, IFN-gamma functions as an anti-inflammatory mediator by promoting the development of regulatory T cells and inhibiting Th17 cell differentiation. IFN-gamma dimers signal through a receptor complex of two IFN-gamma R1 and two IFN-gamma R2 subunits.

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Publications for IFN-gamma (DY285B)(216)

We have publications tested in 5 confirmed species: Human, Mouse, Primate - Presbytis entellus (Indian langur), Transgenic Mouse,  Human.


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Human
(209)
Mouse
(3)
Primate - Presbytis entellus (Indian langur)
(1)
Transgenic Mouse
(1)
 Human
(1)
All Species
Showing Publications 1 - 10 of 216. Show All 216 Publications.
Publications using DY285B Applications Species
Majocchi, S;Lloveras, P;Nouveau, L;Legrand, M;Viandier, A;Malinge, P;Charreton, M;Raymond, C;Pace, E;Millard, B;Svensson, L;Kelpšas, V;Anceriz, N;Salgado-Pires, S;Daubeuf, B;Magistrelli, G;Gueneau, F;Moine, V;Masternak, K;Shang, L;Fischer, N;Ferlin, W; NI-3201 Is a Bispecific Antibody Mediating PD-L1-Dependent CD28 Co-stimulation on T Cells for Enhanced Tumor Control Cancer Immunology Research 2025-01-06 [PMID: 39760515] (Human) Human
Xue, X;Gajic, ZZ;Caragine, CM;Legut, M;Walker, C;Kim, JYS;Wang, X;Yan, RE;Wessels, HH;Lu, C;Bapodra, N;Gürsoy, G;Sanjana, NE; Paired CRISPR screens to map gene regulation in cis and trans bioRxiv : the preprint server for biology 2024-11-27 [PMID: 39651170] (Human) Human
Shepelkova, GS;Evstifeev, VV;Berezovskiy, YS;Ergeshova, AE;Tarasov, RV;Bagirov, MA;Yeremeev, VV; Characteristics of Pulmonary Inflammation in Patients with Different Forms of Active Tuberculosis International journal of molecular sciences 2024-11-02 [PMID: 39519346] (Human) Human
Sedloev, D;Chen, Q;Unglaub, JM;Schanda, N;Hao, Y;Besiridou, E;Neuber, B;Schmitt, A;Raffel, S;Liu, Y;Janssen, M;Müller-Tidow, C;Schmitt, M;Sauer, T; Proteasome inhibition enhances the anti-leukemic efficacy of chimeric antigen receptor (CAR) expressing NK cells against acute myeloid leukemia Journal of hematology & oncology 2024-09-16 [PMID: 39285441] (Human) Human
Malek, E;Rana, PS;Swamydas, M;Daunov, M;Miyagi, M;Murphy, E;Ignatz-Hoover, JJ;Metheny, L;Kim, SJ;Driscoll, JJ; The TGF? type I receptor kinase inhibitor vactosertib in combination with pomalidomide in relapsed/refractory multiple myeloma: a phase 1b trial Nature communications 2024-08-27 [PMID: 39191755] (Human) Human
Jacobs, MME;Maas, RJF;Jonkman, I;Negishi, Y;Tielemans Zamora, W;Yanginlar, C;van Heck, J;Matzaraki, V;Martens, JHA;Baltissen, M;Vermeulen, M;Morla-Folch, J;Ranzenigo, A;Wang, W;Umali, M;Ochando, J;van der Vlag, J;Hilbrands, LB;Joosten, LAB;Netea, MG;Mulder, WJM;van Leent, MMT;Mhlanga, MM;Teunissen, AJP;Rother, N;Duivenvoorden, R; Trained immunity is regulated by T cell-induced CD40-TRAF6 signaling Cell reports 2024-08-22 [PMID: 39178113] (Human) Human
Pascual-Pasto, G;McIntyre, B;Hines, MG;Giudice, AM;Garcia-Gerique, L;Hoffmann, J;Mishra, P;Matlaga, S;Lombardi, S;Shraim, R;Schürch, PM;Yarmarkovich, M;Hofmann, TJ;Alikarami, F;Martinez, D;Tsang, M;Gil-de-Gómez, L;Spear, TT;Bernt, KM;Wolpaw, AJ;Dimitrov, DS;Li, W;Bosse, KR; CAR T-cell-mediated delivery of bispecific innate immune cell engagers for neuroblastoma Nature communications 2024-08-21 [PMID: 39164224] (Human) Human
Schiemann, K;Belousova, N;Matevossian, A;Nallaparaju, KC;Kradjian, G;Pandya, M;Chen, Z;Aral, E;Krauel, EM;Petrova, E;Boesler, C;Kitzing, T;Lecomte, M;Wagner, C;Blayo, AL;Schann, S;Huck, B;Moisan, J;Zaynagetdinov, R; Dual A2A/ A2B adenosine receptor antagonist M1069 counteracts immuno-suppressive mechanisms of adenosine and reduces tumor growth in vivo Molecular cancer therapeutics 2024-08-20 [PMID: 39162025] (Human) Human
Deng, J;Pan, T;Wang, D;Hong, Y;Liu, Z;Zhou, X;An, Z;Li, L;Alfano, G;Li, G;Dolcetti, L;Evans, R;Vicencio, JM;Vlckova, P;Chen, Y;Monypenny, J;Gomes, CAC;Weitsman, G;Ng, K;McCarthy, C;Yang, X;Hu, Z;Porter, JC;Tape, CJ;Yin, M;Wei, F;Rodriguez-Justo, M;Zhang, J;Tejpar, S;Beatson, R;Ng, T; The MondoA-dependent TXNIP/GDF15 axis predicts oxaliplatin response in colorectal adenocarcinomas EMBO molecular medicine 2024-08-05 [PMID: 39103698] (Human) Human
Gaifem, J;Rodrigues, CS;Petralia, F;Alves, I;Leite-Gomes, E;Cavadas, B;Dias, AM;Moreira-Barbosa, C;Revés, J;Laird, RM;Novokmet, M;Štambuk, J;Habazin, S;Turhan, B;Gümü?, ZH;Ungaro, R;Torres, J;Lauc, G;Colombel, JF;Porter, CK;Pinho, SS; A unique serum IgG glycosylation signature predicts development of Crohn's disease and is associated with pathogenic antibodies to mannose glycan Nature immunology 2024-07-30 [PMID: 39080486] (Human) Human
Show All 216 Publications.

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Product General Protocols

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FAQs for IFN-gamma (DY285B). (Showing 1 - 1 of 1 FAQs).

  1. Is Recombinant Human IFN-gamma Protein - Clinical grade or preclinical ?
    • We are research use only.

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Early T cell response is associated with mild COVID-19 and rapid SARS-CoV-2 clearance
Jamshed Arslan, Pharm D, PhD SARS-CoV-2 induces both humoral and cellular immunity. A vaccine or natural infection invokes SARS-CoV-2-specific humoral components (antibodies from activated B cells) and cellular resp...  Read full blog post.


  Read full blog post.

Success of combined IL-10 and IL-12 therapy in colon cancer depends on IFN-gamma and gut barrier integrity
By Jamshed Arslan, Pharm. D., PhD. Colon cancer is responsible for over 600,000 deaths per year worldwide. Colon cancer can be classified into two categories: mismatch repair (MMR)-deficient and MMR-proficient cancers...  Read full blog post.

You complete me: Natural killer cells need TGF-beta inhibition to effectively combat cancers
By Jamshed Arslan Pharm.D. Natural killer (NK) cells are lymphocytes of the innate immune system that were first discovered for their “natural” ability to kill cancer cells. To use NK cells as anti-cancer therapy, t...  Read full blog post.

iNOS: The Nitric Oxide Boss
Nitric oxide (NO) is an inorganic, gaseous, and reactive free radical that acts as a biologic mediator in processes such as neurotransmission, vasorelaxation, and cytotoxicity. In addition, it has antimicrobial and anti-tumoral activities. NO producti...  Read full blog post.

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