Human GM-CSF Quantikine ELISA Kit

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

GM-CSF (Granulocyte-Macrophage Colony Stimulating Factor) induces the development of monocytes, neutrophils, eosinophils, and myeloid and dermal dendritic cells. It also acts as a neutrophil and dendritic cell chemoattractant. GM-CSF promotes Th1 and Th17 cell mediated autoimmune inflammation as well as the inflammatory activation of dendritic cells, microglia, alveolar macrophages, and eosinophils. In addition, it cooperates with G-CSF in promoting tumor cell proliferation and invasion. GM-CSF signals through a receptor complex composed of GM-CSF R alpha and the Common beta Chain (beta c) with Syndecan-2 as a potential co-receptor. The beta c subunit is shared by the receptor complexes for IL-3 and IL-5.

We have publications tested in 4 confirmed species: Human, Mouse, Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque), Rabbit.

We have publications tested in 1 application: ELISA Capture.

Showing Publications 1 - 10 of 57. Show All 57 Publications. Collapse Publications.

Publications using DGM00	Applications	Species
F Parween, SP Singh, HH Zhang, N Kathuria, FA Otaizo-Car, A Shamsaddin, PJ Gardina, S Ganesan, J Kabat, HA Lorenzi, TG Myers, JM Farber Chemokine positioning determines mutually exclusive roles for their receptors in extravasation of pathogenic human T cells bioRxiv : the preprint server for biology, 2023-02-13;0(0):. 2023-02-13 [PMID: 36789428] (Human)		Human
C Papagoras, S Tsiami, A Chrysantho, I Mitroulis, X Baraliakos Serum granulocyte-macrophage colony-stimulating factor (GM-CSF) is increased in patients with active radiographic axial spondyloarthritis and persists despite anti-TNF treatment Arthritis Research & Therapy, 2022-08-16;24(1):195. 2022-08-16 [PMID: 35974380] (Human)		Human
N Jirapongwa, S Thongchot, W Chiraphapp, T Chieochans, D Sa-Nguanra, M Warnnissor, P Thuwajit, PT Yenchitsom, C Thuwajit Mesothelin?specific T cell cytotoxicity against triple negative breast cancer is enhanced by 40s ribosomal protein subunit 3?treated self?differentiated dendritic cells Oncology reports, 2022-05-26;48(1):. 2022-05-26 [PMID: 35616135] (Human)		Human
AV Smirnov, GV Kontsevaya, TA Shnaider, AM Yunusova, NA Feofanova, LA Gerlinskay, IA Serova, OL Serov, NR Battulin Evaluation of the alpha-casein (CSN1S1) locus as a potential target for a site-specific transgene integration Scientific Reports, 2022-05-14;12(1):7983. 2022-05-14 [PMID: 35568783] (Mouse)		Mouse
S Zhang, D Dong, Y Zhang, J Wang, L Liu, Y Zhao miR-124-3p relieves allergic rhinitis by inhibiting dipeptidyl peptidase-4 International immunopharmacology, 2021-10-26;101(0):108279. 2021-10-26 [PMID: 34715574] (Human)		Human
B Cao, M Liu, J Huang, J Zhou, J Li, H Lian, W Huang, Y Guo, S Yang, L Lin, M Cai, C Zhi, J Wu, L Liang, Y Hu, H Hu, J He, B Liang, Q Zhao, K Zhu Development of mesothelin-specific CAR NK-92 cells for the treatment of gastric cancer International journal of biological sciences, 2021-09-03;17(14):3850-3861. 2021-09-03 [PMID: 34671203] (Human)		Human
W Gao, Z Jin, Y Zheng, Y Xu Psoralen inhibits the inflammatory response and mucus production in allergic rhinitis by inhibiting the activator protein�1 pathway and the downstream expression of cystatin?SN Molecular Medicine Reports, 2021-07-19;24(3):. 2021-07-19 [PMID: 34278468] (Human)		Human
F Zhou, P Liu, H Lv, Z Gao, W Chang, Y Xu miR-31 attenuates murine allergic rhinitis by suppressing interleukin-13-induced nasal epithelial inflammatory responses Mol Med Rep, 2020-11-12;23(1):. 2020-11-12 [PMID: 33179116] (Human)		Human
M Drill, KL Powell, LK Kan, NC Jones, TJ O'Brien, JA Hamilton, M Monif Inhibition of purinergic P2X receptor 7 (P2X7R) decreases granulocyte-macrophage colony-stimulating factor (GM-CSF) expression in U251 glioblastoma cells Sci Rep, 2020-09-09;10(1):14844. 2020-09-09 [PMID: 32908225] (Human)		Human
DH Kim, A Gu, JS Lee, EJ Yang, A Kashif, MH Hong, G Kim, BS Park, SJ Lee, IS Kim Suppressive effects of S100A8 and S100A9 on neutrophil apoptosis by cytokine release of human bronchial epithelial cells in asthma Int J Med Sci, 2020-02-04;17(4):498-509. 2020-02-04 [PMID: 32174780] (Human)		Human
T Sun, M Ju, X Dai, H Dong, W Gu, Y Gao, R Fu, X Liu, Y Huang, W Liu, Y Chi, W Wang, H Li, Y Zhou, L Shi, R Yang, L Zhang Multilevel defects in the hematopoietic niche in essential thrombocythemia Haematologica, 2019-07-09;0(0):. 2019-07-09 [PMID: 31289202] (Human)		Human
D Hao, X Wen, L Liu, L Wang, X Zhou, Y Li, X Zeng, G He, X Jiang Sanshool improves UVB-induced skin photodamage by targeting JAK2/STAT3-dependent autophagy Cell Death Dis, 2019-01-08;10(1):19. 2019-01-08 [PMID: 30622245] (Human)		Human
K Huang, L Ran, W Wang, R Zhou, X Cai, R Li, Y Li, C Zhou, W He, R Wang Glucocorticoid insensitivity by staphylococcal enterotoxin B in keratinocytes of allergic dermatitis is associated with impaired nuclear translocation of the Glucocorticoid Receptor ? J. Dermatol. Sci., 2018-11-26;92(3):272-280. 2018-11-26 [PMID: 30522881] (Human)		Human
V Kemp, DJM van den Wo, MGM Camps, T van Hall, P Kinderman, N Pronk-van, RC Hoeben Arming oncolytic reovirus with GM-CSF gene to enhance immunity Cancer Gene Ther., 2018-11-23;0(0):. 2018-11-23 [PMID: 30467340]
G Jordakieva, I Grabovac, E Valic, KE Schmidt, A Graff, A Schuster, K Hoffmann-S, C Oberhuber, O Scheiner, A Goll, J Godnic-Cva Occupational exposure to ultrafine particles in police officers: no evidence for adverse respiratory effects J Occup Med Toxicol, 2018-02-03;13(0):5. 2018-02-03 [PMID: 29434649] (ELISA Capture, Human)	ELISA Capture	Human
F Reggiani, V Labanca, P Mancuso, C Rabascio, G Talarico, S Orecchioni, A Manconi, F Bertolini Adipose progenitor cell secretion of GM-CSF and MMP9 promotes a stromal and immunological microenvironment that supports breast cancer progression Cancer Res., 2017-07-28;0(0):. 2017-07-28 [PMID: 28754674] (Human)		Human
YH Sun, L He, MY Yan, RQ Zhao, B Li, F Wang, Y Yang, HP Yu Overexpression of GLP-1 receptors suppresses proliferation and cytokine release by airway smooth muscle cells of patients with chronic obstructive pulmonary disease via activation of ABCA1 Mol Med Rep, 2017-05-25;0(0):. 2017-05-25 [PMID: 28560433]
Ingrid C Weel Association between Placental Lesions, Cytokines and Angiogenic Factors in Pregnant Women with Preeclampsia PLoS ONE, 2016-06-17;11(6):e0157584. 2016-06-17 [PMID: 27315098] (Human)		Human
Pundir P, MacDonald C, Kulka M The Novel Receptor C5aR2 Is Required for C5a-Mediated Human Mast Cell Adhesion, Migration, and Proinflammatory Mediator Production. J Immunol, 2015-08-17;195(6):2774-87. 2015-08-17 [PMID: 26283482] (Human)		Human
Spampinato S, Obermeier B, Cotleur A, Love A, Takeshita Y, Sano Y, Kanda T, Ransohoff R Sphingosine 1 Phosphate at the Blood Brain Barrier: Can the Modulation of S1P Receptor 1 Influence the Response of Endothelial Cells and Astrocytes to Inflammatory Stimuli? PLoS ONE, 2015-07-21;10(7):e0133392. 2015-07-21 [PMID: 26197437] (Human)		Human
Park S, Breitbach C, Lee J, Park J, Lim H, Kang W, Moon A, Mun J, Sommermann E, Maruri Avidal L, Patt R, Pelusio A, Burke J, Hwang T, Kirn D, Park Y Phase 1b Trial of Biweekly Intravenous Pexa-Vec (JX-594), an Oncolytic and Immunotherapeutic Vaccinia Virus in Colorectal Cancer. Mol Ther, 2015-06-15;23(9):1532-40. 2015-06-15 [PMID: 26073886] (Human)		Human
Rudisch A, Dewhurst M, Horga L, Kramer N, Harrer N, Dong M, van der Kuip H, Wernitznig A, Bernthaler A, Dolznig H, Sommergruber W High EMT Signature Score of Invasive Non-Small Cell Lung Cancer (NSCLC) Cells Correlates with NFkappaB Driven Colony-Stimulating Factor 2 (CSF2/GM-CSF) Secretion by Neighboring Stromal Fibroblasts. PLoS ONE, 2015-04-28;10(4):e0124283. 2015-04-28 [PMID: 25919140] (Human)		Human
Huang , Yao-Huei, Yang , Pei-Ming, Chuah , Qiu-Yu, Lee , Yi-Jang, Hsieh , Yi-Fen, Peng , Chih-Wen, Chiu , Shu-Jun Autophagy promotes radiation-induced senescence but inhibits bystander effects in human breast cancer cells. Autophagy, 2014-04-30;10(7):1212-28. 2014-04-30 [PMID: 24813621] (Human)		Human
Sawada H, Saito T, Nickel N, Alastalo T, Glotzbach J, Chan R, Haghighat L, Fuchs G, Januszyk M, Cao A, Lai Y, Perez V, Kim Y, Wang L, Chen P, Spiekerkoetter E, Mitani Y, Gurtner G, Sarnow P, Rabinovitch M Reduced BMPR2 expression induces GM-CSF translation and macrophage recruitment in humans and mice to exacerbate pulmonary hypertension. J Exp Med, 2014-01-20;211(2):263-80. 2014-01-20 [PMID: 24446489] (Human)		Human
Dickinson R, Milne P, Jardine L, Zandi S, Swierczek S, McGovern N, Cookson S, Ferozepurwalla Z, Langridge A, Pagan S, Gennery A, Heiskanen-Kosma T, Hamalainen S, Seppanen M, Helbert M, Tholouli E, Gambineri E, Reykdal S, Gottfreethsson M, Thaventhiran J, Morris E, Hirschfield G, Richter A, Jolles S, Bacon C, Hambleton S, Haniffa M, Bryceson Y, Allen C, Prchal J, Dick J, Bigley V, Collin M The evolution of cellular deficiency in GATA2 mutation. Blood, 2013-12-17;123(6):863-74. 2013-12-17 [PMID: 24345756] (Human)		Human
Smrz D, Bandara G, Beaven M, Metcalfe D, Gilfillan A Prevention of F-actin assembly switches the response to SCF from chemotaxis to degranulation in human mast cells. Eur J Immunol, 2013-06-04;43(7):1873-82. 2013-06-04 [PMID: 23616175] (Human)		Human
Chen C, Duckworth C, Zhao Q, Pritchard D, Rhodes J, Yu L Increased circulation of galectin-3 in cancer induces secretion of metastasis-promoting cytokines from blood vascular endothelium. Clin Cancer Res, 2013-02-11;19(7):1693-704. 2013-02-11 [PMID: 23401226] (Human)		Human
Houser KR, Johnson DK, Ishmael FT Anti-inflammatory effects of methoxyphenolic compounds on human airway cells. J Inflamm (Lond), 2012-03-13;9(0):6. 2012-03-13 [PMID: 22414048] (Human)		Human
Freund A, Patil CK, Campisi J p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype. EMBO J., 2011-03-11;30(8):1536-48. 2011-03-11 [PMID: 21399611] (Human)		Human
Huang SJ, Zenclussen AC, Chen CP, Basar M, Yang H, Arcuri F, Li M, Kocamaz E, Buchwalder L, Rahman M, Kayisli U, Schatz F, Toti P, Lockwood CJ The implication of aberrant GM-CSF expression in decidual cells in the pathogenesis of preeclampsia. Am. J. Pathol., 2010-09-09;177(5):2472-82. 2010-09-09 [PMID: 20829438] (Human)		Human
Beziat V, Nguyen S, Exley M, Achour A, Simon T, Chevallier P, Sirvent A, Vigouroux S, Debre P, Rio B, Vieillard V, Lubrano-Berthelier C, Alatrakchi N Shaping of iNKT cell repertoire after unrelated cord blood transplantation. Clin. Immunol., 2010-02-13;135(3):364-73. 2010-02-13 [PMID: 20153980] (Human)		Human
Calmy A, Gayet-Ageron A, Montecucco F, Nguyen A, Mach F, Burger F, Ubolyam S, Carr A, Ruxungtham K, Hirschel B, Ananworanich J HIV increases markers of cardiovascular risk: results from a randomized, treatment interruption trial. AIDS, 2009-05-15;23(8):929-39. 2009-05-15 [PMID: 19425222] (Human)		Human
Schuster C, Vaculik C, Fiala C, Meindl S, Brandt O, Imhof M, Stingl G, Eppel W, Elbe-Burger A HLA-DR+ leukocytes acquire CD1 antigens in embryonic and fetal human skin and contain functional antigen-presenting cells. J. Exp. Med., 2009-01-12;206(1):169-81. 2009-01-12 [PMID: 19139172] (Human)		Human
Hartl D, Krauss-Etschmann S, Koller B, Hordijk PL, Kuijpers TW, Hoffmann F, Hector A, Eber E, Marcos V, Bittmann I, Eickelberg O, Griese M, Roos D Infiltrated neutrophils acquire novel chemokine receptor expression and chemokine responsiveness in chronic inflammatory lung diseases. J. Immunol., 2008-12-01;181(11):8053-67. 2008-12-01 [PMID: 19017998] (Human)		Human
Aranha CC, Gupta SM, Reddy KV Assessment of cervicovaginal cytokine levels following exposure to microbicide Nisin gel in rabbits. Cytokine, 2008-05-29;43(1):63-70. 2008-05-29 [PMID: 18513989] (Rabbit)		Rabbit
Sorrentino A, Ferracin M, Castelli G, Biffoni M, Tomaselli G, Baiocchi M, Fatica A, Negrini M, Peschle C, Valtieri M Isolation and characterization of CD146+ multipotent mesenchymal stromal cells. Exp. Hematol., 2008-05-27;36(8):1035-46. 2008-05-27 [PMID: 18504067] (Human)		Human
Makowska JS, Grzegorczyk J, Bienkiewicz B, Wozniak M, Kowalski ML Systemic responses after bronchial aspirin challenge in sensitive patients with asthma. J. Allergy Clin. Immunol., 2007-12-20;121(2):348-54. 2007-12-20 [PMID: 18086495] (Human)		Human
Hatfield K, Ryningen A, Corbascio M, Bruserud O Microvascular endothelial cells increase proliferation and inhibit apoptosis of native human acute myelogenous leukemia blasts. Int. J. Cancer, 2006-11-15;119(10):2313-21. 2006-11-15 [PMID: 16921487] (Human)		Human
Vassina EM, Yousefi S, Simon D, Zwicky C, Conus S, Simon HU cIAP-2 and survivin contribute to cytokine-mediated delayed eosinophil apoptosis. Eur. J. Immunol., 2006-07-01;36(7):1975-84. 2006-07-01 [PMID: 16761316] (Human)		Human
Pang L, Nie M, Corbett L, Sutcliffe A, Knox AJ Mast cell beta-tryptase selectively cleaves eotaxin and RANTES and abrogates their eosinophil chemotactic activities. J. Immunol., 2006-03-15;176(6):3788-95. 2006-03-15 [PMID: 16517749] (Human)		Human
Anderson ST, Williams AJ, Brown JR, Newton SM, Simsova M, Nicol MP, Sebo P, Levin M, Wilkinson RJ, Wilkinson KA Transmission of Mycobacterium tuberculosis undetected by tuberculin skin testing. Am. J. Respir. Crit. Care Med., 2006-02-02;173(9):1038-42. 2006-02-02 [PMID: 16456140] (Human)		Human
Bartemes KR, Cooper KM, Drain KL, Kita H Secretory IgA induces antigen-independent eosinophil survival and cytokine production without inducing effector functions. J. Allergy Clin. Immunol., 2005-10-01;116(4):827-35. 2005-10-01 [PMID: 16210057] (Human)		Human
Ameredes BT, Calhoun WJ Modulation of GM-CSF release by enantiomers of beta-agonists in human airway smooth muscle. J. Allergy Clin. Immunol., 2005-07-01;116(1):65-72. 2005-07-01 [PMID: 15990776] (Human)		Human
Kahlon KS, Brown C, Cooper LJ, Raubitschek A, Forman SJ, Jensen MC Specific recognition and killing of glioblastoma multiforme by interleukin 13-zetakine redirected cytolytic T cells. Cancer Res., 2004-12-15;64(24):9160-6. 2004-12-15 [PMID: 15604287] (Human)		Human
Chen LL, Tager IB, Peden DB, Christian DL, Ferrando RE, Welch BS, Balmes JR Effect of ozone exposure on airway responses to inhaled allergen in asthmatic subjects. Chest, 2004-06-01;125(6):2328-35. 2004-06-01 [PMID: 15189958] (Human)		Human
Henkel JS, Engelhardt JI, Siklos L, Simpson EP, Kim SH, Pan T, Goodman JC, Siddique T, Beers DR, Appel SH Presence of dendritic cells, MCP-1, and activated microglia/macrophages in amyotrophic lateral sclerosis spinal cord tissue. Ann. Neurol., 2004-02-01;55(2):221-35. 2004-02-01 [PMID: 14755726] (Human)		Human
Xiao T, Fujita H, Saeki H, Mitsui H, Sugaya M, Tada Y, Kakinuma T, Torii H, Nakamura K, Asahina A, Tamaki K Thymus and activation-regulated chemokine (TARC/CCL17) produced by mouse epidermal Langerhans cells is upregulated by TNF-alpha and IL-4 and downregulated by IFN-gamma. Cytokine, 2003-08-01;23(4):126-32. 2003-08-01 [PMID: 12967648] (Human)		Human
Lamming CE, 175, Augustin L, Blackstad M, Lund TC, Hebbel RP, Verfaillie CM Spontaneous circulation of myeloid-lymphoid-initiating cells and SCID-repopulating cells in sickle cell crisis. 2003-03-01;111(6):811-9. 2003-03-01 [PMID: 12639987] (Human)		Human
Hellman C, 107334, Hallden G, Hylander B, Lundahl J Regulation of the interleukin-5 receptor alpha-subunit on peripheral blood eosinophils from healthy subjects. Lagging strand gap suppression connects BRCA-mediated fork protection to nucleosome assembly through PCNA-dependent CAF-1 recycling, 2003-01-01;131(1):75-81. 2003-01-01 [PMID: 12519389] (Human)		Human
Qu C, Moran TM, Randolph GJ Autocrine type I IFN and contact with endothelium promote the presentation of influenza A virus by monocyte-derived APC. J. Immunol., 2003-01-15;170(2):1010-8. 2003-01-15 [PMID: 12517968] (Human)		Human
de Revel T, Becard N, Sorg T, Rousseau S, Spano JP, Thiebot H, Methali M, Gras G, Le Grand R, Dormont D Retroviral interleukin 1alpha gene transfer in bone marrow stromal cells in a primate model: induction of myelopoiesis stimulation. Br. J. Haematol., 2002-09-01;118(3):875-84. 2002-09-01 [PMID: 12181061] (Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque))		Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
Pages F, Lebel-Binay S, Vieillefond A, Deneux L, Cambillau M, Soubrane O, Debre B, Tardy D, Lemonne JL, Abastado JP, Fridman WH, Thiounn N Local immunostimulation induced by intravesical administration of autologous interferon-gamma-activated macrophages in patients with superficial bladder cancer. Clin. Exp. Immunol., 2002-02-01;127(2):303-9. 2002-02-01 [PMID: 11876754] (Human)		Human
Loeuillet C, Bernard G, Remy-Martin J, Saas P, Herve P, Douay L, Chalmers D Distinct hematopoietic support by two human stromal cell lines. Exp. Hematol., 2001-06-01;29(6):736-45. 2001-06-01 [PMID: 11378269] (Human)		Human
Sato E, Koyama S Bleomycin stimulates lung fibroblast and epithelial cell lines to release eosinophil chemotactic activity. Eur. Respir. J., 2000-11-01;16(5):951-8. 2000-11-01 [PMID: 11153598] (Human)		Human
Szabowski A, Maas-Szabowski N, Andrecht S, Kolbus A, Schorpp-Kistner M, Fusenig NE, Angel P c-Jun and JunB antagonistically control cytokine-regulated mesenchymal-epidermal interaction in skin. Cell, 2000-11-22;103(5):745-55. 2000-11-22 [PMID: 11114331] (Human)		Human
Kadowaki N, Antonenko S, Lau JY, Liu YJ Natural interferon alpha/beta-producing cells link innate and adaptive immunity. J. Exp. Med., 2000-07-17;192(2):219-26. 2000-07-17 [PMID: 10899908] (Human)		Human
Chopra V, Dinh TV, Hannigan EV Serum levels of interleukins, growth factors and angiogenin in patients with endometrial cancer. J. Cancer Res. Clin. Oncol., 1997-01-01;123(3):167-72. 1997-01-01 [PMID: 9119882] (Human)		Human
Show All 57 Publications. Collapse Publications.

Array DGM00

• GM-CSF Antibodies
• GM-CSF Antibody Pairs
• GM-CSF ELISA Kits
• GM-CSF Lysate
• GM-CSF Proteins
• GM-CSF ELISAs
• GM-CSF Proteins and Enzymes