I am looking for an ovine antibody for bFGF and PDGF-AB and ELISA Kits for both. It is for a research work on meniscus healing in sheep. Do you have anything suitable? How is the homology with sheep? Is it ever tested and/or published in papers?

Name: Human FGF basic/FGF2/bFGF Quantikine HS ELISA Kit
Brand: Novus Biologicals
SKU: HSFB00D
Price: 675 USD

Question

Accepted Answer

Unfortunately, most of the products you are interested in have not yet been tested in sheep, but this should not be a problem, due to sequence homology, and our Innovators Reward Program. In terms of an antibody for bFGF, also called FGF-2, we have several antibodies that are validated to detect the bovine protein, which is almost identical to that from sheep (99% homology). We only have FGF2 ELISA kits that have been tested with human or mouse. Mouse FGF-2 has 94% homology with sheep; human has 98% homology for most of its sequence, but also has an additional stretch of amino acids that is not present in the sheep protein. I therefore think that the mouse kit would be most suitable, just in case the human kit targets the region of the human protein not present in mouse. We sell antibodies to PDGF-A or PDGF-B rather than PDGF-AB. We don't have any PDGF-A antibodies that have been tested in sheep but there are several options you may find of interest. There isn't a sheep PDGFA sequence in UniProt, so I can't comment on how similar it is to the PDGFA from other species. Nevertheless, our  NBP1-52533 PDGFB antibody has been shown to work in sheep. We sell two PDGF-AB ELISA kits , but these are for human and rat. I'm not sure how well these would work with sheep. Note that if you test a product with a species (or application) that it has not yet been validated in, you are eligible for our Innovator's Reward: Novus would provide you a 50% refund on the purchased product as well as a 50% discount on a future product of equal or lesser value. You would email innovators@novusbio.com to apply for your award, and we

At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Reactivity	HuSpecies Glossary
Applications	ELISA
Conjugate	HRP

Catalog# & Conjugate	Size	Price
HRP SSFB00D

HRP PHSFB00D

Conjugate	Catalog #	Availability	Size	Price
HRP	SSFB00D
HRP	PHSFB00D

Background	The Quantikine HS Human FGF basic Immunoassay kit is a 5.5 hour solid phase ELISA designed to measure FGF basic levels in serum, plasma, and urine. It contains E. coli-expressed recombinant human FGF basic and antibodies raised against the recombinant factor. It has been shown to quantitate recombinant human FGF basic accurately. Results obtained using natural human FGF basic showed... linear curves that were parallel to the standard curves obtained using the Quantikine HS kit standards. These results indicate that this kit can be used to determine relative mass values for natural human FGF basic. Show More
Specificity	Natural and recombinant human FGF basic
Source	N/A
Inter-Assay	See PDF Datasheet for details
Intra-Assay	See PDF Datasheet for details
Spike Recovery	See PDF Datasheet for details
Sample Volume	See PDF Datasheet for details
Gene	FGF2

Human FGF basic/FGF2/bFGF Quantikine HS ELISA Kit

Species Glossary

Images

Product Details

Order Details

Human FGF basic/FGF2/bFGF Quantikine HS ELISA Kit Summary

Applications/Dilutions

Packaging, Storage & Formulations

Notes

Alternate Names for Human FGF basic/FGF2/bFGF Quantikine HS ELISA Kit

Background

Customers Who Viewed This Item Also Viewed...

Publications for FGF basic/FGF2/bFGF (HSFB00D)(17)

Reviews for FGF basic/FGF2/bFGF (HSFB00D) (0)

Product General Protocols

FAQs for FGF basic/FGF2/bFGF (HSFB00D). (Showing 1 - 1 of 1 FAQs).

Additional FGF basic/FGF2/bFGF Products

Blogs on FGF basic/FGF2/bFGF

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Review this Product

Bioinformatics

Publications using HSFB00D	Applications	Species
Ueno, K;Kurazumi, H;Suzuki, R;Yanagihara, M;Mizoguchi, T;Harada, T;Morikage, N;Hamano, K; miR-709 exerts an angiogenic effect through a FGF2 upregulation induced by a GSK3B downregulation Scientific reports 2024-05-18 [PMID: 38762650] (Human)		Human
J Sikovanyec, M Vincze, I Földesi, G Németh, Z Kozinszky Angiogenic factors measured in aspirated placental tissue between the 10?+?6 and 18?+?3 weeks of gestation Reproductive biology, 2021-11-16;21(4):100572. 2021-11-16 [PMID: 34798517] (Human)		Human
Briasoulis , Evangelo, Aravantinos , Gerasimo, Kouvatseas , George, Pappas , Periklis, Biziota , Eirini, Sainis , Ioannis, Makatsoris , Thomas, Varthalitis , Ioannis, Xanthakis , Ioannis, Vassias , Antonios, Klouvas , George, Boukovinas , Ioannis, Fountzilas , George, Syrigos , Kostanti, Kalofonos , Haralamb, Samantas , Epaminon Dose selection trial of metronomic oral vinorelbine monotherapy in patients with metastatic cancer: a hellenic cooperative oncology group clinical translational study. BMC Cancer, 2013-05-29;13(1):263. 2013-05-29 [PMID: 23718900] (Human)		Human
Llovet JM, Pena CE, Lathia CD, Shan M, Meinhardt G, Bruix J, Pallota MG, Zarba JJ, Boyer M, Riordan S, Strickland A, Tebbutt N, Thomson B, Borbath I, De Greve J, Van Laethem J-, Van Steenbergen W, Van Vlierberghe H, Barrios C, Cosme de Oliveira A, Kotzev I, Takov D, Tchernev K, Burak K, Ma M, Metrakos P, Olweny C, Sherman M, Gamargo Garate C, Martinez-Castillo J, Beaugrand M, Bennouna J, Blanc J-, Bronowicki J-, Degos F, Dominguez S, Grange J-, Hillon P, Raoul J-, Seitz J-, Blum H, Buggisch P, Caspary W, Dollinger M, Gerken G, Goke B, Gregor M, Greten T, Haussinger D, Hilgard P, ScherÃƒÂ¼bl J, Scheulen M, Schmid R, Spengler U, Wiest R, Zeuzem S, Arvanitakis C, Germanidis G, Katsos I, Figer A, Stemmer S, Amadori D, Bolondi L, Cognetti F, Craxi A, Farinati F, Gridelli C, Martoni A, Mazzaferro V, Porta C, Ricci S, Sangiovanni A, Santoro A, Trevisani F, Cisnero Garza LE, Gane E, O'Donnell A, Leon J, Lozano A, Jassem J, Rydzewska G, Szawlowski A, Tomczak P, Badulescu F, Miron L, Kubyshkin V, Bruix J, Forner A, Bustamante Schneider J, Diago M, Montero Alvarez JL, Pascual S, RuÃƒÂz del Arbol L, Sangro B, SolÃƒÂ¡ R, Tabernero J, Muellhaupt B, Roth A, Jeffry Evans TR, Falk S, Meyer T, Reeves H, Ross P, Befeler A, Boyer T, Britten C, Byrne T, Garcia-Tsao G, Gold P, Goldenberg A, Heuman D, Kennedy P, Koch A, Llovet JM, Marrero J, Schilsky M, Schwartz J, Schwartz M Plasma biomarkers as predictors of outcome in patients with advanced hepatocellular carcinoma. Clin. Cancer Res., 2012-02-28;18(8):2290-300. 2012-02-28 [PMID: 22374331] (Human)		Human
Schirmer SH, van Royen N, Moerland PD, Fledderus JO, Henriques JP, van der Schaaf RJ, Vis MM, Baan J, Koch KT, Horrevoets AJ, Hoefer IE, Piek JJ Local cytokine concentrations and oxygen pressure are related to maturation of the collateral circulation in humans. J. Am. Coll. Cardiol., 2009-06-09;53(23):2141-7. 2009-06-09 [PMID: 19497439] (Human)		Human
Kanter J, Khan SY, Kelher M, Gore L, Silliman CC Oncogenic and angiogenic growth factors accumulate during routine storage of apheresis platelet concentrates. Clin. Cancer Res., 2008-06-15;14(12):3942-7. 2008-06-15 [PMID: 18559616] (Human)		Human
Weiner L, Han R, Scicchitano BM, Li J, Hasegawa K, Grossi M, Lee D, Brissette JL Dedicated epithelial recipient cells determine pigmentation patterns. Cell, 2007-09-07;130(5):932-42. 2007-09-07 [PMID: 17803914] (Mouse)		Mouse
Anagnostopoulos A, Eleftherakis-Papaiakovou V, Kastritis E, Tsionos K, Bamias A, Meletis J, Dimopoulos MA, Terpos E Serum concentrations of angiogenic cytokines in Waldenstrom macroglobulinaemia: the ration of angiopoietin-1 to angiopoietin-2 and angiogenin correlate with disease severity. Br. J. Haematol., 2007-06-01;137(6):560-8. 2007-06-01 [PMID: 17451406] (Human)		Human
Wedgwood S, Devol JM, Grobe A, Benavidez E, Azakie A, Fineman JR, Black SM Fibroblast growth factor-2 expression is altered in lambs with increased pulmonary blood flow and pulmonary hypertension. Pediatr. Res., 2007-01-01;61(1):32-6. 2007-01-01 [PMID: 17211137] (Ovine)		Ovine
Schneider P, Vasse M, Corbiere C, Legrand E, Marie-Cardine A, Boquet C, Cazin L, Vannier JP Endostatin variations in childhood acute lymphoblastic leukaemia--comparison with basic fibroblast growth factor and vascular endothelial growth factor. Leuk. Res., 2006-09-29;31(5):629-38. 2006-09-29 [PMID: 17011029] (Human)		Human
Kulke MH, Bergsland EK, Ryan DP, Enzinger PC, Lynch TJ, Zhu AX, Meyerhardt JA, Heymach JV, Fogler WE, Sidor C, Michelini A, Kinsella K, Venook AP, Fuchs CS Phase II study of recombinant human endostatin in patients with advanced neuroendocrine tumors. J. Clin. Oncol., 2006-08-01;24(22):3555-61. 2006-08-01 [PMID: 16877721] (Human)		Human
Bourlev V, Larsson A, Olovsson M Elevated levels of fibroblast growth factor-2 in serum from women with endometriosis. Am. J. Obstet. Gynecol., 2006-03-01;194(3):755-9. 2006-03-01 [PMID: 16522409] (Human)		Human
Mross K, Drevs J, Muller M, Medinger M, Marme D, Hennig J, Morgan B, Lebwohl D, Masson E, Ho YY, Gunther C, Laurent D, Unger C Phase I clinical and pharmacokinetic study of PTK/ZK, a multiple VEGF receptor inhibitor, in patients with liver metastases from solid tumours. Eur. J. Cancer, 2005-06-01;41(9):1291-9. 2005-06-01 [PMID: 15939265] (Human)		Human
Lacoste E, Martineau I, Gagnon G Platelet concentrates: effects of calcium and thrombin on endothelial cell proliferation and growth factor release. J. Periodontol., 2003-10-01;74(10):1498-507. 2003-10-01 [PMID: 14653397] (Human)		Human
Huang SF, t?DüÝ ˆ!Û, Kim SJ, Ž˜™ ¢§r«C, Lee AT, Karashima T, Bucana C, Kedar D, Sweeney P, Mian B, Fan D, Shepherd D, Fidler IJ, Dinney CP, Killion JJ Inhibition of growth and metastasis of orthotopic human prostate cancer in athymic mice by combination therapy with pegylated interferon-alpha-2b and docetaxel. beta ¨ïÛ›Jyþ¢×677SªµÛT¹Vñ¥óÊøhÍŸì5Û, 2002-10-15;62(20):5720-6. 2002-10-15 [PMID: 12384530] (Mouse)		Mouse
Esner M, D†ÃÅê†Ò, Pachernik J, Hampl A, Dvorak P Targeted disruption of fibroblast growth factor receptor-1 blocks maturation of visceral endoderm and cavitation in mouse embryoid bodies. ÎÎ¶)Š4wJ]¾b.ŠKd•ÿ¶fäMò&¨k³, 2002-09-01;46(6):817-25. 2002-09-01 [PMID: 12382948] (Bovine)		Bovine
Allen DK, Waters DJ, Knapp DW, Kuczek T High urine concentrations of basic fibroblast growth factor in dogs with bladder cancer. J. Vet. Intern. Med., 1996-07-01;10(4):231-4. 1996-07-01 [PMID: 8819047] (Canine)		Canine
Show All 17 Publications. Collapse Publications.