Human ErbB3/Her3 DuoSet ELISA, 15 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

ErbB3, also called Her3 (human epidermal growth factor receptor 3) in humans, is a type I transmembrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors. ErbB3 binds neuregulins NRG1 and NRG2, but lacks a working kinase domain; heterodimerization with another ErbB receptor is required for signaling. ErbB3 is important in development of Schwann cells, neural crest cells, heart valves and the sympathetic nervous system. When expressed with ErbB2 in breast, skin, ovary and gastrointestinal tumors, ErbB3 is a potent mitogen.

We have publications tested in 1 confirmed species: Human.

Showing Publications 1 - 4 of 4.

Publications using DY348	Applications	Species
D Gutsch, R Jenke, T Büch, A Aigner Inhibition of HER Receptors Reveals Distinct Mechanisms of Compensatory Upregulation of Other HER Family Members: Basis for Acquired Resistance and for Combination Therapy Cells, 2021-01-29;10(2):. 2021-01-29 [PMID: 33572976] (Human)		Human
Heregulin-1� and HER3 in hepatocellular carcinoma: status and regulation by insulin J Exp Clin Cancer Res, 2016-08-11;35(1):126. 2016-08-11 [PMID: 27514687] (Human)		Human
Patritumab plus trastuzumab and paclitaxel in human epidermal growth factor receptor 2-overexpressing metastatic breast cancer Cancer Sci., 2016-09-15;107(10):1465-1470. 2016-09-15 [PMID: 27452985] (Human)		Human
Lin SH, Lee YC, Choueiri MB, Wen S, Mathew P, Ye X, Do KA, Navone NM, Kim J, Tu SM, Yu-Lee LY, Logothetis CJ Soluble ErbB3 levels in bone marrow and plasma of men with prostate cancer. Clin. Cancer Res., 2008-06-15;14(12):3729-36. 2008-06-15 [PMID: 18559590] (Human)		Human

Array DY348

• ErbB3/Her3 Antibodies
• ErbB3/Her3 Antibody Pairs
• ErbB3/Her3 ELISA Kit
• ErbB3/Her3 Lysates
• ErbB3/Her3 Proteins
• ErbB3/Her3 Proteins and Enzymes
• ErbB3/Her3 ELISAs