Home » HSPB8/HSP22 » HSPB8/HSP22 Antibodies » HSPB8/HSP22 Antibody (3C12-H11) [Alexa Fluor® 405]
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HSPB8/HSP22 Antibody (3C12-H11) [Alexa Fluor® 405]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC
Clone
3C12-H11
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 405

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 488
NBP1-48303AF488
Alexa Fluor 647
NBP1-48303AF647
Alexa Fluor 700
NBP1-48303AF700
Biotin
NBP1-48303B
DyLight 350
NBP1-48303UV
DyLight 405
NBP1-48303V
DyLight 488
NBP1-48303G
DyLight 550
NBP1-48303R
DyLight 650
NBP1-48303C
DyLight 680
NBP1-48303FR
DyLight 755
NBP1-48303IR
FITC
NBP1-48303F
HRP
NBP1-48303H
Janelia Fluor 549
NBP1-48303JF549
Janelia Fluor 646
NBP1-48303JF646
Unconjugated
NBP1-48303
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HSPB8/HSP22 Antibody (3C12-H11) [Alexa Fluor® 405] Summary

Immunogen
His-tagged human recombinant HSP22
Localization
Cytoplasm , Nucleus
Specificity
Detects approx 22kDa. Does not cross react with alpha crystallin.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
HSPB8
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Alternate Names for HSPB8/HSP22 Antibody (3C12-H11) [Alexa Fluor® 405]

  • Alpha-crystallin C chain
  • CMT2L
  • CRYAC
  • DHMN2
  • E2IG1
  • E2IG1E2-induced gene 1 protein
  • H11
  • H11DHMN2
  • heat shock 22kDa protein 8
  • heat shock 27kDa protein 8
  • heat shock protein beta-8
  • HMN2
  • HMN2A
  • HSP22
  • HSP22CMT2L
  • HSPB8
  • Protein kinase H11
  • Small stress protein-like protein HSP22

Background

HSP22 is encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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HSPB8/HSP22
Antibody (3C12-H11) [ ...
NBP1-48303AF405
HSPB8/HSP22 Antibody (3C12-H11) [Alexa Fluor® 405]
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol HSPB8