Hemoglobin zeta Antibody (778633) Summary
Immunogen |
E. coli-derived recombinant human Hemoglobin zeta Met1-Arg142 Accession # P02008 |
Specificity |
Detects human Hemoglobin zeta in direct ELISAs. |
Source |
N/A |
Isotype |
IgG2b |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
HBZ |
Purity Statement |
Protein A or G purified from hybridoma culture supernatant |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunocytochemistry 8-25 ug/mL
- Western Blot 0.2 ug/mL
|
Packaging, Storage & Formulations
Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. - 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
|
Buffer |
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS. |
Preservative |
No Preservative |
Concentration |
LYOPH |
Reconstitution Instructions |
Sterile PBS to a final concentration of 0.5 mg/mL. |
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Hemoglobin zeta Antibody (778633)
Background
Hemoglobin is a tetrameric
heme-containing protein that is responsible for the transport of oxygen by red
blood cells in the circulation. For most of fetal development and adulthood,
hemoglobin consists of two alpha chains and two beta chains. Hemoglobin zeta (HBZ)
is an approximately 15 kDa alpha chain-like protein that is produced during the first few
weeks of embryogenesis until the onset of alpha chain expression. Its
expression is prolonged in a0-thalassemia which is characterized by deficient alpha
chain production. The Gower-1, Portland-1, and Portland-2 forms of hemoglobin
consist of two zeta chains in association with either two epsilon, gamma, or beta
chains, respectively. Human Hemoglobin zeta shares 79% amino acid sequence
identity with mouse and rat Hemoglobin zeta.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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