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HARS2 Antibody (OTI5H2) [Janelia Fluor® 585]

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Product Details

Summary
Reactivity Hu, Ca, Pm, PmSpecies Glossary
Applications WB, Flow, IHC, CyTOF-ready
Clone
OTI5H2
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 585

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HARS2 Antibody (OTI5H2) [Janelia Fluor® 585] Summary

Immunogen
Full length human recombinant protein of human HARS2(NP_036340) produced in HEK293T cell.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
HARS2
Purity
Immunogen affinity purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for HARS2 Antibody (OTI5H2) [Janelia Fluor® 585]

  • EC 6.1.1
  • EC 6.1.1.21
  • HARSLprobable histidyl-tRNA synthetase, mitochondrial
  • HARS-related
  • HARSRhistidine tRNA ligase 2, mitochondrial (putative)
  • HisRS
  • histidine translase
  • Histidine--tRNA ligase
  • Histidine--tRNA ligase-like
  • histidyl-tRNA synthetase 2, mitochondrial (putative)
  • histidyl-tRNA synthetase-like
  • HO3histidine-tRNA ligase homolog

Background

The HARS2 gene encodes a 506 amino acid, 56kDA probable histidine--tRNA ligase (mitochondrial) protein that is member to the II family of aminoacyl-tRNA synthetases which charge tRNA with cognate amino acids. The HARS2 gene is located in a head-to-head orientation with HARS on chromosome 5, which is the location of where homologous genes share a bidirectional promoter. The protein works as an accessory in the regulation of protein biosynthesis through the synthesis of histidyl-transfer RNA. HARS2 is involved in gene expression and mitochondrian tRNA aminoacylation and has been known to interact with genes ICT1, AARS2, AASS, ABSB7, and ACAD9. HARS2 has been investigated in immunodeficiency, malaria, pneumonia, hearing loss, tuberculosis, schizophrenia, and ovarian dysgenesis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol HARS2