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GSAP Antibody [Janelia Fluor® 585]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Janelia Fluor 585

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GSAP Antibody [Janelia Fluor® 585] Summary

Immunogen
GSAP antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human GSAP. The immunogen is located within amino acids 770 - 820 of GSAP. Amino Acid Squence: RNHVTRLLQNYKKQPRNSM
Specificity
Multiple isoforms of GSAP are known to exist. GSAP antibody is predicted to not cross-react with other F-box protein family members.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PION
Purity
Peptide affinity purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Peptide affinity purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for GSAP Antibody [Janelia Fluor® 585]

  • GSAP
  • pigeon homolog (Drosophila)
  • PION
  • tcag7.1314

Background

Gamma secretase activating protein (GSAP) is implicated in Alzheimer's disease, through instigating plaque formation of amyloid beta. Immunohistochemistry to identify GSAP in brain can demonstrate its abundance in certain regions of damage, and is usually morphologically changed throughout the progression of Alzheimer's disease. GSAP can be used as a qualitative biomarker of Alzheimer's disease progression, and is regularly considered one of the best targets of therapies to diminish the effects of Alzheimer's disease in affected individuals.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for GSAP Antibody (NBP2-81894JF585) (0)

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Secondary Antibodies

 

Isotype Controls

Additional GSAP Products

Array NBP2-81894JF585

Research Areas for GSAP Antibody (NBP2-81894JF585)

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Bioinformatics

Gene Symbol PION