Glyoxalase I Antibody (9F11) [PE]

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Product Details

Summary
Reactivity All-NASpecies Glossary
Applications WB, ELISA, Flow, ICC/IF
Clone
9F11
Clonality
Monoclonal
Host
Mouse
Conjugate
PE

Order Details

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Glyoxalase I Antibody (9F11) [PE] Summary

Immunogen
Synthetic Methylglyoxal modified Keyhole Limpet Hemocyanin (KLH).
Specificity
Specific for Methylglyoxal modified proteins. Does not detect free Methylglyoxal. Does not cross-react with Acrolein, Hexanoyl Lysine, Malondialdeyhde, 4-Hydroxy-2-hexenal, 4-Hydroxy nonenal, or Crotonaldehyde modified proteins.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
GLO1
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Alternate Names for Glyoxalase I Antibody (9F11) [PE]

  • Aldoketomutase
  • EC 4.4.1.5
  • GLO1
  • GLOD1
  • Glx I
  • GLYI
  • glyoxalase domain containing 1
  • Glyoxalase I
  • glyoxalase Ialdoketomutase
  • Ketone-aldehyde mutase
  • lactoyl glutathione lyase
  • lactoylglutathione lyase
  • Methylglyoxalase
  • S-D-lactoylglutathione methylglyoxal lyase

Background

Lactoylglutathione lyase, also known as GLO1, is a member of the glyoxalase I family that is responsible for the catalysis and formation of S-lactoyl-glutathione from methylglyoxal condensation and reduced glutatione. It is believed that inactivation of GLO1 in endothelial cells contributes to vascular complications in diabetes. GLO1 has also been shown to extend lifespan in C. elegans, and has been shown to be upregulated in malignant cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Glyoxalase I Antibody (NBP2-59369PE) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol GLO1