Glut3 Antibody

Glucose is the major source of our energy and there are numerous isoforms of the glucose transporter in mammals, including Glut1, Glut2, Glut3, Glut4, Glut5, Glut6, Glut7, Glut8 and Glut9. The Glut5 gene located on the short arm of human chromosome 1 encodes a 501-amino acid facilitative glucose transporter. Glut5 mRNA is highly expressed in small intestine and to a lesser extent in kidney, skeletal muscle and adipose tissue. Glut5 plays a critical role in fructose absorption in the small intestine and its expression is highly induced when exposed to a fructose-enriched diet. Glut5 transporter expressed in human skeletal muscle is specifically localized to the plasma membrane, where it participates in regulating hexose transfer across the sarcolemma. Glut8, a novel glucose transporter-like protein, exhibits significant sequence similarity with the other members of sugar transporter family. Glut8 comprises 12 putative membrane-spanning helices and several conserved motifs, which are important for transport activity. In human tissues, Glut8 is predominantly expressed in testis and, to a lesser extent, in most other tissues including skeletal muscle, heart, small intestine and brain. In addition, the Glut8 glucose transport facilitator has a hormonally regulated testicular function.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: IF/IHC, WB.

Showing Publications 1 - 3 of 3.

Publications using NBP1-89762	Applications	Species
Bertelli PM, Pedrini E, Hughes D et al. Long term high glucose exposure induces premature senescence in retinal endothelial cells Frontiers in Physiology 2022-08-26 [PMID: 36091370]
Theodosakis N, Held MA, Marzuka-Alcala A et al. BRAF inhibition decreases cellular glucose uptake in melanoma in association with reduction in cell volume. Mol. Cancer Ther. 2015-05-06 [PMID: 25948295] (WB, Human)	WB	Human
Wang W, Xiao ZD, Li X et al. AMPK modulates Hippo pathway activity to regulate energy homeostasis. Nat Cell Biol 2015-04-01 [PMID: 25751139] (IF/IHC, Human)	IF/IHC	Human

Array NBP1-89762

• Glut3 Antibodies
• Glut3 ELISA Kits
• Glut3 Proteins