GLI-3 Antibody - BSA Free

Gli-3 (also known as Zinc Finger Protein Gli-3 or GLI-Kruppel family member GLI-3) belongs to the GLI C2H2-type zinc-finger protein family and contains 5 C2H2-type zinc fingers. Gli-3 is very important for normal limb and brain development and is implicated in the transduction of Shh signal. Gli-3 is a nuclear protein expressed in a wide variety of normal adult tissues, including lung, colon, spleen, placenta, testis, and myometrium. Defects in Gli-3 are the cause of Greig cephalo-polysyndactyly syndrome (GCPS); an autosomal dominant disorder-affecting limb and craniofacial development. Two isoforms of human Gli-3 have been reported. One is the full length protein at ~170-190kDa and the other is a truncated isoform at ~80kDa.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 application: IHC-P.

Showing Publications 1 - 3 of 3.

Publications using NBP2-29627	Applications	Species
Jackson DA, Smith TD, Amarsaikhan N et al. Modulation of the IL-6 Receptor alpha Underlies GLI2-Mediated Regulation of Ig Secretion in Waldenstrom Macroglobulinemia Cells. J Immunol 2015-09-15 [PMID: 26238488]
Bowers C Nutraceutical Inhibition of Hedgehog Signaling in Pancreatic Cancer Thesis 1905-07-13
Burleson M, Deng JJ, Qin T Et al. GLI3 Is Stabilized by SPOP Mutations and Promotes Castration Resistance via Functional Cooperation with Androgen Receptor in Prostate Cancer Molecular cancer research : MCR 2021-10-05 [PMID: 34610962] (IHC-P)	IHC-P

Images	Ratings	Applications	Species	Date	Details
Enlarge	4 reviewed by: Zhihui Zhu	WB	Mouse	07/09/2019	View Summary Application Western Blot Sample Tested Adult mouse brain tissue,mouse brain lysates Species Mouse Lot A-1 Comments Comments mice brain samples for western blot.

Array NBP2-29627

• GLI-3 Antibodies
• GLI-3 Proteins