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GCAP1 Antibody

Images

 
Immunohistochemistry-Paraffin: GCAP1 Antibody [NBP2-55158] - Staining of human liver shows no positivity in hepatocytes as expected.
Immunohistochemistry-Paraffin: GCAP1 Antibody [NBP2-55158] - Staining of human duodenum shows no positivity in glandular cells as expected.
Immunohistochemistry-Paraffin: GCAP1 Antibody [NBP2-55158] -Staining of human retina shows moderate to strong positivity in photoreceptor layer as well as outer plexiform layer.
Immunohistochemistry-Paraffin: GCAP1 Antibody [NBP2-55158] -Staining of human skeletal muscle shows no positivity in myocytes as expected.

Product Details

Summary
Reactivity Hu, Pm, RtSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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GCAP1 Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: EYVAALSLVLKGKVEQKLRWYFKLYDVDGNGCIDRDELLTIIQAIRAINPCSDTTMTAEEFTDTVFSKIDVNGDGELSLEEFIEGVQKDQMLLDTLTRSLDLTRIVRRLQNGEQDEEGADEAAEAAG
Predicted Species
Rat (90%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GUCA1A
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:5000 - 1:10000
  • Immunohistochemistry-Frozen Reported in scientific literature (PMID:35024589)
  • Immunohistochemistry-Paraffin 1:5000 - 1:10000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended..
Control Peptide
GCAP1 Recombinant Protein Antigen (NBP2-55158PEP)
Publications
Read Publication using
NBP2-55158 in the following applications:

Reactivity Notes

Use in Monkey reported in scientific literature (PMID:35024589). Mouse( 88%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for GCAP1 Antibody

  • C6orf131
  • chromosome 6 open reading frame 131
  • CORD14
  • GCAP 1
  • GCAP1photoreceptor 1
  • GCAPGUCA
  • guanylate cyclase activator 1A (retina)
  • Guanylate cyclase activator 1A
  • guanylin 1, retina
  • guanylyl cyclase-activating protein 1
  • GUCA1

Background

The GCAP1 gene plays a role in the recovery of retinal photoreceptors from photobleaching. In the recovery phase, thephototransduction messeneger cGMP is replenished by retinal guanylyl cyclase-1 (GC1). GC1 is activated by decreasingCa(2+) concentrations follo

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for GCAP1 Antibody (NBP2-55158)(1)

We have publications tested in 1 confirmed species: Monkey.

We have publications tested in 1 application: IHC-Fr.


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IHC-Fr
(1)
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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol GUCA1A