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GABA-AR alpha 2 Antibody

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Genetic Strategies: Western Blot: GABA-A R alpha 2 Antibody [NBP2-36560] - Western blot of mouse brain lysates from wild type (Control) and alpha2-knockout (alpha2-K/O) animals showing specific immunolabeling of ...read more

Product Details

Summary
Reactivity Mu, Hu, Rt, Bv, Ca, Pm, ZeSpecies Glossary
Applications WB, ICC/IF, IHC, KO
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
     

Genetic Strategies

   

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GABA-AR alpha 2 Antibody Summary

Immunogen
Fusion protein from the cytoplasmic loop of the alpha 2 subunit. Accession # P23576
Specificity
Specific for endogenous levels of the ~51 kDa alpha 2-subunit of the GABAA receptor in Western blots. Labeling is absent in alpha 2-subunit knockout animals.
Predicted Species
Human (100%), Rat (100%), Canine (100%), Primate (100%), Bovine (100%), Zebrafish (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GABRA2
Purity
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 1:1000
  • Immunohistochemistry
  • Knockout Validated
  • Western Blot 1:1000
Application Notes
Use in Immunohistochemistry reported in scientific literature (PMID 28352479).
Theoretical MW
51 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Publications
Read Publications using
NBP2-36560 in the following applications:

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
10mM HEPES (pH 7.5), 0.15M NaCl, 0.1 mg/ml BSA and 50% Glycerol
Preservative
No Preservative
Purity
Antigen Affinity-purified

Alternate Names for GABA-AR alpha 2 Antibody

  • GABA A R alpha 2
  • GABA(A) receptor subunit alpha-2
  • GABAAR alpha 2
  • GABAARa2
  • GABRA2
  • gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • gamma-aminobutyric acid receptor subunit alpha-2

Background

GABA (A) receptors are ligand-gated chloride channels that play a role as inhibitory neurotransmitters. They are known targets for certain classes of environmental and pharmaceutical compounds because a number of drugs interact with binding sites on GABA (A). Some of these drugs include benzodiazepines, anticonvulsants, and anesthetics. GABA (A) Receptors are comprised of subunits and these are further classified into 3 major groups (alpha, beta, and gamma). The subunits determine the pharmacological characteristics.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for GABA-AR alpha 2 Antibody (NBP2-36560)(2)

We have publications tested in 1 confirmed species: Rat.

We have publications tested in 2 applications: IF/IHC, WB.


Filter By Application
IF/IHC
(1)
WB
(1)
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Rat
(1)
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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for GABA-AR alpha 2 Antibody (NBP2-36560) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol GABRA2