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GABA-AR alpha 2 Antibody

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Western Blot: GABA-AR alpha 2 Antibody [NBP2-16566] - Rat tissue extract (50 ug) was separated by 10% SDS-PAGE, and the membrane was blotted with GABA A Receptor alpha 2 antibody [N1C2] diluted at 1:500. The ...read more
Western Blot: GABA-A R alpha 2 Antibody [NBP2-16566] - Sample (30 ug of whole cell lysate) A: NT2D1 10% SDS PAGE gel, diluted at 1:1000.

Product Details

Summary
Reactivity Hu, Rt, Mu, Bv, RM, XpSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

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GABA-AR alpha 2 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human GABA-AR alpha 2. The exact sequence is proprietary.
Localization
Cell junction; synapse; postsynaptic cell membrane; Multi-pass membrane protein; Cell membrane; Multi-pass membrane protein
Predicted Species
Mouse (100%), Rhesus Macaque (100%), Bovine (99%), Xenopus (92%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GABRA2
Purity
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
Theoretical MW
51 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Xenopus laevis (92%).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol
Preservative
0.01% Thimerosal
Purity
Antigen Affinity-purified

Alternate Names for GABA-AR alpha 2 Antibody

  • GABA A R alpha 2
  • GABA(A) receptor subunit alpha-2
  • GABAAR alpha 2
  • GABAARa2
  • GABRA2
  • gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • gamma-aminobutyric acid receptor subunit alpha-2

Background

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol GABRA2
Uniprot