FSHR Antibody (FSHR/1400) [DyLight 488] Summary
Immunogen |
Recombinant human FSHR protein (Uniprot: P23945) |
Localization |
Cytoplasmic & Cell Surface |
Marker |
Ovarian Marker |
Isotype |
IgG1 Kappa |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
FSHR |
Purity |
Protein A or G purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunohistochemistry
- Immunohistochemistry-Paraffin
- Western Blot
|
Application Notes |
Optimal dilution of this antibody should be experimentally determined. |
Packaging, Storage & Formulations
Storage |
Store at 4C in the dark. |
Buffer |
50mM Sodium Borate |
Preservative |
0.05% Sodium Azide |
Purity |
Protein A or G purified |
Alternate Names for FSHR Antibody (FSHR/1400) [DyLight 488]
Background
Follicle-stimulating hormone (FSH), also called follitropin, belongs to the family of glycoprotein hormones that also includes luteininizing hormone and thyroid-stimulating hormone. These hormones are secreted by the pituitary and exist as heterodimers, consisting of a common alpha subunit and a homologous but distinct beta subunit. While the alpha subunit of FSH is involved in the binding of FSH to the receptor, follicle-stimulating hormone receptor (FSHR), the beta subunit stabilizes this interaction. This heterodimer regulates a variety of processes, including secretion, post-translational modification and signal transduction. Both FSH and FSHR are localized to Sertoli cells.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Secondary Antibodies
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