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Frizzled-10 Antibody (tabituximab) - Humanized

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, Flow, Func
Clone
tabituximab
Clonality
Monoclonal
Host
Human
Conjugate
Unconjugated
Concentration
LYOPH

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Frizzled-10 Antibody (tabituximab) - Humanized Summary

Description
Expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.

Also known as 'tabituximab'.

Upon receipt, store immediately at -20C or lower for 24 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles.
Additional Information
Recombinant Monoclonal Antibody
Immunogen
FZD10
Isotype
IgG1
Clonality
Monoclonal
Host
Human
Gene
FZD10
Purity
Protein A purified
Endotoxin Note
< 0.001EU/ug,determined by LAL method.
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Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Functional

Packaging, Storage & Formulations

Storage
Store at 4C.
Buffer
Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)
Preservative
No Preservative
Concentration
LYOPH
Purity
Protein A purified
Reconstitution Instructions
Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.

Alternate Names for Frizzled-10 Antibody (tabituximab) - Humanized

  • CD350 antigen
  • CD350
  • frizzled (Drosophila) homolog 10
  • frizzled homolog 10 (Drosophila)
  • Frizzled10
  • Frizzled-10
  • Fz10
  • FZ-10
  • FZD10
  • FzE7
  • hFz10

Background

Frizzled-10 (FZD10) is a Frizzled Receptor that mediates Wnt signaling. It is expressed during development in embryonic limbs, neural tube, and central nervous system. FZD10 has been reported to be expressed in brain, embryo, kidney, liver, lung, pancreas, placenta, skeletal muscle, spinal cord, and testis. ESTs have been isolated from brain, ear, heart/melanocyte/uterus, and kidney libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol FZD10
Uniprot