FPRL1/FPR2 Antibody [HRP] Summary
Immunogen |
This FPRL1/FPR2 antibody is made to a synthetic peptide from the human FPRL1 protein (between residues 300-350) [UniProt P25090] |
Localization |
Cell membrane; Multi-pass membrane protein. |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Rabbit |
Gene |
FPR2 |
Purity |
Immunogen affinity purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Electron Microscopy
- Flow Cytometry
- Immunocytochemistry/ Immunofluorescence
- Immunohistochemistry
- Immunohistochemistry-Frozen
- Immunohistochemistry-Paraffin
- Western Blot
|
Application Notes |
Optimal dilution of this antibody should be experimentally determined. |
Readout System |
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Reactivity Notes
Rat reactivity reported in scientific literature (PMID: 24086560). Bacteria reactivity reported in scientific literature (PMID: 31234710).
Packaging, Storage & Formulations
Storage |
Store at 4C in the dark. |
Buffer |
PBS |
Preservative |
No Preservative |
Purity |
Immunogen affinity purified |
Alternate Names for FPRL1/FPR2 Antibody [HRP]
Background
Formyl peptide receptor-like receptor 1 (FPRL1), a chemo-attractant receptor also called Lipoxin A4 Receptor (LXA4R), functions as a component of the inflammatory response. The stimulation of FPRL1 results in neutrophil activation and desensitization of chemokine receptors in monocytes (PubMed ID: 11015447). The FPRL1 receptor is up-regulated by interleukin-1 in normal human synovial fibroblasts. The immunodeficiency virus type 1 (HIV-1) envelope protein gp41 can activate the innate host immune cells through FPRL1 and induces directional migration and calcium mobilization in human monocytes and neutrophils. FPRL1 has been reported in phagocytes, monocytes, neutrophils, differentiated myeloid cells from bone marrow, granulocyte HL-60 cells, and synovial fibroblasts. Expressed sequence tags (ESTs) for FPRL1 have been isolated from blood, leukocyte, lung, and placenta libraries. Recently, FPRL1 has been implicated in Alzheimers Disease. Note that Formyl peptide receptor-like receptor 1 (FPRL1) and Formyl peptide receptor 2 (FPR2) are the same, but FPR2 is distinct from FPRL2.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Product General Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
Video Protocols
FAQs for FPRL1/FPR2 Antibody (NLS1878H). (Showing 1 - 1 of 1 FAQ).
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I am looking for an FPRL1 antibody that is reactive to mouse only. Does Novus have the antibody in question?
- To answer your question, unfortunately all our FPRL1 antibodies are polyclonal and would detect both mouse and human formyl peptide receptor-like-1 and we do not have any mouse monoclonal antibody for it.
Secondary Antibodies
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Isotype Controls
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