Western Blot: FoxP2 Antibody [NBP1-86671] - Analysis in human cell line RH-30.
Immunohistochemistry: FoxP2 Antibody [NBP1-86671] - Patterns of neocortical layer markers in the OT. Both CTIP2 and FOXP2 cells were broadly present in Layer 2 and scattered in Layer 3. Dorsal to top, lateral to right. ...read more
Immunohistochemistry-Paraffin: FoxP2 Antibody [NBP1-86671] - Staining of human cerebral cortex shows moderate to strong nuclear positivity in neurons.
Immunohistochemistry-Paraffin: FoxP2 Antibody [NBP1-86671] - Staining of human rectum shows moderate nuclear positivity in glandular cells.
Immunohistochemistry-Paraffin: FoxP2 Antibody [NBP1-86671] - Staining of human skeletal muscle shows no positivity in striated muscle fibers as expected.
Immunohistochemistry-Paraffin: FoxP2 Antibody [NBP1-86671] - Staining of human skin shows moderate nuclear positivity in deep epidermal cells.
Immunocytochemistry/ Immunofluorescence: FoxP2 Antibody [NBP1-86671] - Patterns of neocortical layer markers in the PPC.A) TBR-1 heavily labeled cells in Layer 2 as well as scattered cells in Layer 3. As in the APC many ...read more
Immunocytochemistry/ Immunofluorescence: FoxP2 Antibody [NBP1-86671] - Patterns of neocortical layer markers in the OT.A) TBR-1 (A), BRN2 (D) & CART (E) were only found scattered in the very deepest regions of the OT. ...read more
Immunocytochemistry/ Immunofluorescence: FoxP2 Antibody [NBP1-86671] - Patterns of neocortical layer markers in the APC.A) TBR-1 heavily labeled cells in Layer 2 as well as scattered cells in Layer 3. Of the 4 deep ...read more
Immunocytochemistry/ Immunofluorescence: FoxP2 Antibody [NBP1-86671] - Patterns of neocortical layer markers in the AONpP.A). TBR1-labelled cells were found throughout Layer 2 of the AONpP as well as in the tenia tecta ...read more
This antibody was developed against Recombinant Protein corresponding to amino acids: AQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKASPPITHHS
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
FOXP2
Purity
Immunogen affinity purified
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Rat reactivity reported in scientific literature (PMID: 25926446). Mouse reactivity reported in scientific literature (PMID: 26407299).
Packaging, Storage & Formulations
Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified
Alternate Names for FoxP2 Antibody
CAG repeat protein 44
CAGH44
CAGH44TNRC10forkhead box protein P2
DKFZp686H1726
forkhead box P2
forkhead/winged-helix transcription factor
FoxP2
SPCH1
TNRC10
trinucleotide repeat containing 10
Trinucleotide repeat-containing gene 10 protein
Background
FOXP2 encodes an evolutionarily conserved transcription factor expressed in fetal and adult brain. This transcription factor is a member of the forkhead/winged-helix (FOX) family of transcription factors, and contains a FOX DNA-binding domain and a large polyglutamine tract. Members of the FOX family of transcription factors are regulators of embryogenesis. The product of this gene is thought to be required for proper development of speech and language regions of the brain during embryogenesis. Although a point mutation in this gene has been associated with the KE pedigree segregating developmental verbal dyspraxia, no association between mutations in this gene and another speech disorder, autism, has been found. Four alternative transcripts encoding three different isoforms have been identified.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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