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Flt-3 Ligand/FLT3L Antibody (40406) [Unconjugated]

 (4 Publications)
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Recombinant Human Flt‑3 Ligand/FLT3L (Catalog # 308-FK or 308-FKN) stimulates proliferation in the BaF3 mouse pro‑B cell line transfected with mouse Flt‑3 in a dose-dependent manner (orange line). Proliferation elicited by Recombinant Human Flt‑3 Ligand/FLT3L (5 ng/mL) is neutralized (green line) by increasing concentrations of Human Flt‑3 Ligand/FLT3L Monoclonal Antibody (Catalog # MAB308). The ND50 is typically 0.02‑0.06 µg/mL.
Recombinant Human Flt‑3 Ligand/FLT3L (Catalog # 308-FK or 308-FKN) stimulates proliferation in the BaF3 mouse pro‑B cell line transfected with mouse Flt‑3 in a dose-dependent manner (orange line). ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, B/N
Clone
40406
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

View Available Formulations
Catalog# & Formulation Size Price
Carrier Free
MAB308-SP
Carrier Free
MAB308-500
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Flt-3 Ligand/FLT3L Antibody (40406) [Unconjugated] Summary

Immunogen
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Flt‑3 Ligand/FLT3L
Thr27-Pro185
Accession # AAA17999
Specificity
Detects human Flt-3 Ligand/FLT3L in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant mouse Flt‑3 Ligand/FLT3L is observed.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
FLT3LG
Purity Statement
Protein A or G purified from ascites
Endotoxin Note
<0.10 EU per 1 μg of the antibody by the LAL method.
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • Neutralization 0.02-0.06 ug/mL
  • Western Blot 1 ug/mL
Publications
Read Publications using
MAB308 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Flt-3 Ligand/FLT3L Antibody (40406) [Unconjugated]

  • FL
  • FLG3L
  • Flt3 ligand
  • Flt-3 Ligand
  • Flt3L
  • FLT3LG
  • fms-related tyrosine kinase 3 ligand
  • SL cytokine

Background

Flt-3 Ligand, also known as Flk-2 Ligand, is a transmembrane protein that can be cleaved to release a soluble cytokine. Flt-3 Ligand binds Flt-3 and promotes the growth and differentiation of early hematopoietic progenitor cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Flt-3 Ligand/FLT3L Antibody (MAB308)(4)

We have publications tested in 3 confirmed species: Human, Mouse, Primate - Papio cynocephalus (Yellow Baboon).

We have publications tested in 2 applications: ELISA Development, Neutralization.


Filter By Application
ELISA Development
(2)
Neutralization
(1)
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Human
(1)
Mouse
(1)
Primate - Papio cynocephalus (Yellow Baboon)
(1)
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Reviews for Flt-3 Ligand/FLT3L Antibody (MAB308) (0)

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Bioinformatics

Gene Symbol FLT3LG
Uniprot