FLIP Antibody (7A3D12) - BSA Free

Apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. Acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. Lacks enzymatic (caspase) activity

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publication using NBP2-37359	Applications	Species
Yang X, Zeng Q, Tezel G Regulation of distinct caspase-8 functions in retinal ganglion cells and astroglia in experimental glaucoma Neurobiology of disease 2021-01-09 [PMID: 33434617]

Array NBP2-37359

• FLIP Antibodies
• FLIP ELISA Kits
• FLIP Lysates
• FLIP Proteins
• FLIP Proteins and Enzyme