Fc gamma RIIIB/CD16b Antibody (BLR163J) Summary
Additional Information |
Recombinant Monoclonal |
Immunogen |
residues 21-201 (ECD) |
Clonality |
Monoclonal |
Host |
Rabbit |
Gene |
FCGR3B |
Purity |
>95% |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunocytochemistry/ Immunofluorescence
- Immunohistochemistry
- Western Blot
|
Packaging, Storage & Formulations
Storage |
Store at 2 - 8 C / 1 year from date of receipt |
Buffer |
Borate Buffered Saline (BBS) pH 8.2 with 0.1% BSA and |
Preservative |
0.09% Sodium Azide |
Purity |
>95% |
Alternate Names for Fc gamma RIIIB/CD16b Antibody (BLR163J)
Background
CD16 (FcgRIII) is a 50-65 kDa glycoprotein serving as a low affinity IgG receptor. Human FcgRIII is expressed in two forms FcgRIII-A and -B. FcgRIII-A is a transmembrane protein of monocytes, macrophages, NK cells and a subset of T cells. It is associated with FceRI-g subunit and is responsible for antibody-dependent NK cell cytotoxicity. Mast cell FcgRIII-A is associated, moreover, with FceRI-b subunit. Besides IgG, FceRI-A can be triggered also by oligomeric IgE. FcgRIII-B is a GPI-linked monomeric receptor expressed on neutrophils and is involved in their activation and induction of a proadhesive phenotype.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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FAQs for Fc gamma RIIIB/CD16b Antibody (NBP3-14737) (0)
Secondary Antibodies
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Isotype Controls
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