Species: Hu
Applications: WB, ICC/IF, IHC
Host: Rabbit Monoclonal
Species: Hu
Applications: IHC
Host: Mouse Monoclonal
Species: Hu
Applications: Flow
Host: Rabbit Monoclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: Bioactivity
Species: Hu
Applications: Bioactivity
Species: Hu
Applications: PAGE
Description
CD16 (FcgRIII) is a 50-65 kDa glycoprotein serving as a low affinity IgG receptor. Human FcgRIII is expressed in two forms FcgRIII-A and -B. FcgRIII-A is a transmembrane protein of monocytes, macrophages, NK cells and a subset of T cells. It is associated with FceRI-g subunit and is responsible for antibody-dependent NK cell cytotoxicity. Mast cell FcgRIII-A is associated, moreover, with FceRI-b subunit. Besides IgG, FceRI-A can be triggered also by oligomeric IgE. FcgRIII-B is a GPI-linked monomeric receptor expressed on neutrophils and is involved in their activation and induction of a proadhesive phenotype.
Bioinformatics
Entrez |
Human |
Uniprot |
Human |
Product By Gene ID |
2215 |
Alternate Names |
- CD16
- CD16b antigen
- CD16B
- CD16b
- Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
- Fc fragment of IgG, low affinity IIIb, receptor for (CD16)
- FCG3
- Fc-gamma receptor IIIb (CD 16)
- Fc-gamma RIII
- Fc-gamma RIIIb
- Fc-gamma RIII-beta
- FCGR3
- FcR-10
- fcR-10
- fcRIII
- FcRIII
- FcRIIIb
- fcRIIIb
- IGFR3
- IgG Fc receptor III-1
- low affinity immunoglobulin gamma Fc region receptor III-B
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