Home » EMR3 » EMR3 Antibodies » EMR3 Antibody (908235) [Unconjugated]

EMR3 Antibody (908235) [Unconjugated]

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Human peripheral blood monocytes were stained with Mouse Anti-Human CD14 APC‑conjugated Monoclonal Antibody (Catalog # FAB3832A) and either (A) Mouse Anti-Human EMR3 Monoclonal Antibody (Catalog # MAB8496) or (B) Mouse IgG2B Flow Cytometry Isotype Control (Catalog # MAB0041) followed by Phycoerythrin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0102B).
Human peripheral blood monocytes were stained with Mouse Anti-Human CD14 APC‑conjugated Monoclonal Antibody (Catalog # FAB3832A) and either (A) Mouse Anti-Human EMR3 Monoclonal Antibody (Catalog # MAB8496) or (B) ...read more
EMR3 was detected in immersion fixed paraffin-embedded sections of human lung cancer tissue using Mouse Anti-Human EMR3 Monoclonal Antibody (Catalog # MAB8496) at 5 µg/mL for 1 hour at room temperature ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, IHC, CyTOF-ready
Clone
908235
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB8496U-100UG
Alexa Fluor 405
FAB8496V-100UG
Alexa Fluor 488
FAB8496G-100UG
Alexa Fluor 532
FAB8496X
Alexa Fluor 594
FAB8496T-100UG
Alexa Fluor 647
FAB8496R-100UG
Alexa Fluor 700
FAB8496N-100UG
Alexa Fluor 750
FAB8496S-100UG
Allophycocyanin
FAB8496A-025
Allophycocyanin/Cy7
FAB8496APCCY7
Biotin
FAB8496B
CoraFluor 1
FAB8496CL1
DyLight 350
FAB8496D
DyLight 405
FAB8496E
DyLight 488
FAB8496K
DyLight 550
FAB8496L
DyLight 594
FAB8496M
DyLight 650
FAB8496W
DyLight 680
FAB8496Y
DyLight 755
FAB8496Z
FITC
FAB8496F
HRP
FAB8496H
Janelia Fluor 525
FAB8496JF525
Janelia Fluor 549
FAB8496I
Janelia Fluor 646
FAB8496J
Janelia Fluor 669
FAB8496JF669
PE/Atto594
FAB8496PEATT594
PE/Cy5.5
FAB8496PECY55
PE/Cy7
FAB8496PECY7
PerCP
FAB8496C
mFluor Violet 450 SE
FAB8496MFV450
mFluor Violet 500 SE
FAB8496MFV500
mFluor Violet 610 SE
FAB8496MFV610
View Available Formulations
Catalog# & Formulation Size Price
Carrier Free
FAB8496A-025
Carrier Free
MAB8496-SP
Carrier Free
FAB8496V-100UG
Carrier Free
FAB8496U-100UG
Carrier Free
FAB8496T-100UG
Carrier Free
FAB8496S-100UG
Carrier Free
FAB8496R-100UG
Carrier Free
FAB8496N-100UG
Carrier Free
FAB8496G-100UG
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EMR3 Antibody (908235) [Unconjugated] Summary

Additional Information
Recombinant Monoclonal Antibody.
Immunogen
NS0 mouse myeloma cell line transfected with human EMR3
Met1-Tyr652
Accession # Q9BY15
Specificity
Detects human EMR3 in direct ELISAs.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
EMR3
Purity Statement
Protein A or G purified from cell culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry 0.25 ug/10^6 cells
  • Immunohistochemistry 5-25 ug/mL

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for EMR3 Antibody (908235) [Unconjugated]

  • egf-like module containing, mucin-like, hormone receptor-like 3
  • EGF-like module receptor 3
  • EGF-like module-containing mucin-like hormone receptor-like 3
  • egf-like module-containing mucin-like receptor 3
  • EMR3

Background

EMR3 is a member of the class B seven-span transmembrane (TM7) receptor family. It is expressed predominantly by cells of the immune system, with highest levels in neutrophils, monocytes and macrophages. It may play a role in myeloid-myeloid interactions during immune and inflammatory responses. EMR3 upregulation in glioblastoma multiforme (GBM) is associated with poor survival and may be a potential therapeutic target.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol EMR3
Uniprot