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Elastase Antibody (CELA3B/1257) [FITC]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, IHC, CyTOF-ready
Clone
CELA3B/1257
Clonality
Monoclonal
Host
Mouse
Conjugate
FITC

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Elastase Antibody (CELA3B/1257) [FITC] Summary

Description
This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
Immunogen
Recombinant human Elastase protein fragment (around aa 82-238) (exact sequence is proprietary) (Uniprot: P08861)
Localization
Cytoplasmic
Marker
Pancreatic Function Marker
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
CELA3B
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • ELISA
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Alternate Names for Elastase Antibody (CELA3B/1257) [FITC]

  • CBPP
  • cholesterol-binding pancreatic protease
  • chymotrypsin-like elastase family member 3B
  • chymotrypsin-like elastase family, member 3B
  • E1
  • EC 3.4.21
  • EC 3.4.21.70
  • EL-1
  • ELA3B
  • elastase 1
  • elastase 3B, pancreatic
  • Elastase IIIB
  • elastase-3B
  • fecal elastase 1
  • pancreatic elastase 1
  • pancreatic endopeptidase E
  • Protease E
  • proteinase E

Background

Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have sixelastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike otherelastases, elastase 3B has little elastolytic activity. Like most of the human elastases, elastase 3B is secreted fromthe pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has adigestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. Elastase 3Bmay also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B havebeen referred to as protease E and as elastase 1, and excretion of this protein in fecal material is frequently usedas a measure of pancreatic function in clinical assays. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CELA3B