Elastase Products

Description

Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have sixelastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike otherelastases, elastase 3B has little elastolytic activity. Like most of the human elastases, elastase 3B is secreted fromthe pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has adigestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. Elastase 3Bmay also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B havebeen referred to as protease E and as elastase 1, and excretion of this protein in fecal material is frequently usedas a measure of pancreatic function in clinical assays. (provided by RefSeq)

Bioinformatics

Entrez	1991 Human 23436 Human
Uniprot	AAH05216 Human NM_007352 Human P08246 Human
Product By Gene ID	23436
Alternate Names	CBPP cholesterol-binding pancreatic protease chymotrypsin-like elastase family member 3B chymotrypsin-like elastase family, member 3B E1 EC 3.4.21 EC 3.4.21.70 EL-1 ELA3B elastase 1 elastase 3B, pancreatic Elastase IIIB elastase-3B Elastase-3B fecal elastase 1 pancreatic elastase 1 pancreatic endopeptidase E Protease E proteinase E

Research Areas for Elastase

Find related products by research area and learn more about each of the different research areas below.

Cancer
Neuroscience