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ELAC2 Antibody

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Immunohistochemistry;ELAC2 Antibody[NBP3-30497]Detection of human ELAC2 by immunohistochemistry. Sample: FFPE section of human stomach. Antibody: Affinity purified rabbit anti-ELAC2 used at a dilution of 1:1,000 . Detection: DAB
Immunohistochemistry;ELAC2 Antibody[NBP3-30497]Detection of human ELAC2 by immunohistochemistry. Sample: FFPE section of human stomach. Antibody: Affinity purified rabbit anti-ELAC2 used at a dilution of 1:1,000 . ...read more
Immunohistochemistry;ELAC2 Antibody[NBP3-30514]Detection of mouse ELAC2 by immunohistochemistry. Sample: FFPE section of mouse plasmacytoma. Antibody: Affinity purified rabbit anti-ELAC2 used at a dilution of 1:1,000 . ...read more

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, IHC, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

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ELAC2 Antibody Summary

Immunogen
Between 776 and 826
Assay Type
[Assay Type]
Sample Volume
[Sample Volume]
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ELAC2
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-citrate/phosphate pH 7 -8.
Preservative
0.09% Sodium Azide
Purity
Affinity purified

Alternate Names for ELAC2 Antibody

  • EC 3.1.26.11
  • elaC homolog 2 (E. coli)
  • ElaC homolog protein 2
  • ELC2
  • FLJ10530
  • FLJ36693
  • FLJ42848
  • Heredity prostate cancer protein 2
  • HPC2elaC (E. coli) homolog 2
  • putative prostate cancer susceptibility protein HPC2/ELAC2
  • Ribonuclease Z 2
  • RNase Z 2
  • tRNA 3 endonuclease 2
  • tRNase Z (long form)
  • tRNase Z 2
  • zinc phosphodiesterase ELAC protein 2

Background

The protein encoded by the ELAC2 gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity,which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activatedSmad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expressioncan suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased riskof prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene. (providedby RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol ELAC2