EDNRB/Endothelin R Type B Antibody (671917) [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

EDNRB (Endothelin Receptor Type B) is a 50-55 kDa member of the beta-family of rhodopsin receptors. It binds endothelin 1, 2 and 3, and is found on endothelial cells where it mediates vasodilation. Mature human EDNRB is a 7-transmembrane glycoprotein that is 416 amino acids (aa) in length. It contains a 75 aa N-terminal extracellular region (aa 27-101), and a 44 aa C-terminal cytoplasmic domain. There are three EDNRB variants that affect aa 27-101. One shows a 90 aa N-terminal extension, a second shows the same 90 aa N-terminal substitution coupled with a deletion of aa 268-398, and a third shows proteolytic cleavage between Arg64‑Ser65. Over aa 27-101, human EDNRB shares 67% and 97% aa identity with mouse and canine EDNRB, respectively.     

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Showing Publication 1 - 1 of 1.

Publication using MAB4496	Applications	Species
Yuan Y, Leiby KL, Greaney AM et al. A Pulmonary Vascular Model From Endothelialized Whole Organ Scaffolds Frontiers in Bioengineering and Biotechnology 2021-11-19 [PMID: 34869270]

Array MAB4496

• EDNRB/Endothelin R Type B Antibodies
• EDNRB/Endothelin R Type B ELISA Kit
• EDNRB/Endothelin R Type B Lysates
• EDNRB/Endothelin R Type B Protein