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EAR2/NR2F6 Antibody (N2025) [Unconjugated]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC, IP
Clone
N2025
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

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EAR2/NR2F6 Antibody (N2025) [Unconjugated] Summary

Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
NR2F6
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 5-15 ug/mL
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

Storage
Store the unopened product at -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Buffer
A liquid formulation in physiologic saline with 0.1% NaN3.
Preservative
0.1% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for EAR2/NR2F6 Antibody (N2025) [Unconjugated]

  • EAR2
  • EAR-2ERBA-related gene-2
  • EAR2nuclear receptor subfamily 2 group F member 6
  • ERBAL2
  • ERBAL2v-erb-a avian erythroblastic leukemia viral oncogene homolog-like 2
  • NR2F6
  • nuclear receptor subfamily 2, group F, member 6
  • V-erbA-related protein 2

Background

EAR2 (COUP TF-gamma, ERBAL2; NR2F6) is a member of the orphan nuclear receptor family. No ligand has been reported. Expression is detected in fetal liver, placenta, heart, muscle, and pancreas. No expression of EAR2 was detected in lung and brain tissue. Interaction of EAR2 with the transcription factor CBFA2 reveals a negative regulator of granulocyte differentiation. Knock out of EAR2 has been shown to affect forebrain clock and nociception in mice. EAR2 has also been shown to suppress transcription of luteinizing hormone receptor (LHR).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol NR2F6