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Dtk/TYRO3 Antibody (109646) [DyLight 550]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB, ELISA, ELISA(Cap), ELISA(Det), ICC/IF
Clone
109646
Clonality
Monoclonal
Host
Rat
Conjugate
DyLight 550

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 532
FAB759X
Biotin
BAM759
DyLight 350
FAB759D
DyLight 405
FAB759E
DyLight 488
FAB759K
DyLight 594
FAB759M
DyLight 650
FAB759W
DyLight 680
FAB759Y
DyLight 755
FAB759Z
FITC
FAB759F
HRP
FAB759H
Janelia Fluor 549
FAB759I
Janelia Fluor 646
FAB759J
PerCP
FAB759C
Unconjugated
MAB759
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB759
Carrier Free
MAB759
Carrier Free
MAB759-SP
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Dtk/TYRO3 Antibody (109646) [DyLight 550] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse Tyro3/Dtk
Ala31-Ser418
Accession # P55144
Specificity
Detects mouse Tyro3/Dtk extracellular domain in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human Tyro3/Dtk, recombinant mouse (rm) Mer, or rmAxl is observed.
Isotype
IgG1
Clonality
Monoclonal
Host
Rat
Gene
TYRO3
Purity
Protein A or G purified from hybridoma culture supernatant
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Applications/Dilutions

Dilutions
  • ELISA Capture (Matched Antibody Pair)
  • ELISA Detection (Matched Antibody Pair)
  • ELISA Standard (Matched Pair)
  • Immunocytochemistry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Dtk/TYRO3 Antibody (109646) [DyLight 550]

  • Brt
  • BYK
  • Dtk
  • EC 2.7.10
  • EC 2.7.10.1
  • FLJ16467
  • Rse
  • Sky
  • Tif
  • TYRO3 protein tyrosine kinase
  • Tyro3
  • Tyrosine-protein kinase byk
  • Tyrosine-protein kinase DTK
  • tyrosine-protein kinase receptor TYRO3
  • Tyrosine-protein kinase RSE
  • Tyrosine-protein kinase SKY

Background

Receptor protein tyrosine kinases (RPTKs) are a class of transmembrane signaling molecules. They have been shown to regulate signaling cascades that control synaptic function in the central nervous system (CNS). Tyro3 is one of three RPTKs belonging to the Axl/UFO subfamily, that also includes Axl and Mer. Tyro3 is the most commonly expressed of these receptors in the CNS. It may be involved in the cell adhesion process, and is commonly found in adult tissues with expression mostly in brain, testis, vascular and lymphatic tissue.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol TYRO3