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Drosha Antibody [Janelia Fluor® 635]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Janelia Fluor 635

Order Details

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Drosha Antibody [Janelia Fluor® 635] Summary

Immunogen
Produced in rabbits immunized with a synthetic peptide corresponding to the center region of the Human Drosha.
Predicted Species
Mouse (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DROSHA
Purity
Antigen and protein A Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Antigen and protein A Affinity-purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Drosha Antibody [Janelia Fluor® 635]

  • drosha, double-stranded RNA-specific endoribonuclease
  • drosha, ribonuclease type III
  • EC 3.1.26.3
  • ETOHI2
  • nuclear RNase III Drosha
  • p241
  • Protein Drosha
  • putative protein p241 which interacts with transcription factor Sp1
  • putative ribonuclease III
  • RANSE3L
  • ribonuclease 3
  • Ribonuclease III
  • ribonuclease III, nuclear
  • RN3nuclear
  • RNase III

Background

Members of the ribonuclease III superfamily of double-stranded (ds) RNA-specific endoribonucleases participate in diverse RNA maturation and decay pathways in eukaryotic and prokaryotic cells (Fortin et al., 2002 [PubMed 12191433]). The RNase III Drosha is the core nuclease that executes the initiation step of microRNA (miRNA) processing in the nucleus (Lee et al., 2003 [PubMed 14508493]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol DROSHA