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Dopamine D1R/DRD1 Antibody (887438) [CoraFluor™ 1]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, IHC, CyTOF-ready
Clone
887438
Clonality
Monoclonal
Host
Mouse
Conjugate
CoraFluor 1

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB8276U-100UG
Alexa Fluor 405
FAB8276V-100UG
Alexa Fluor 488
FAB8276G-100UG
Alexa Fluor 532
FAB8276X
Alexa Fluor 594
FAB8276T-100UG
Alexa Fluor 647
FAB8276R-100UG
Alexa Fluor 700
FAB8276N-100UG
Alexa Fluor 750
FAB8276S-100UG
Allophycocyanin
FAB8276A
Allophycocyanin/Cy7
FAB8276APCCY7
Biotin
FAB8276B
DyLight 350
FAB8276D
DyLight 405
FAB8276E
DyLight 488
FAB8276K
DyLight 550
FAB8276L
DyLight 594
FAB8276M
DyLight 650
FAB8276W
DyLight 680
FAB8276Y
DyLight 755
FAB8276Z
FITC
FAB8276F
HRP
FAB8276H
Janelia Fluor 525
FAB8276JF525
Janelia Fluor 549
FAB8276I
Janelia Fluor 585
FAB8276JF585
Janelia Fluor 635
FAB8276JF635
Janelia Fluor 646
FAB8276J
Janelia Fluor 669
FAB8276JF669
PE/Atto594
FAB8276PEATT594
PE/Cy5.5
FAB8276PECY55
PE/Cy7
FAB8276PECY7
PerCP
FAB8276C
Unconjugated
MAB8276
mFluor Violet 450 SE
FAB8276MFV450
mFluor Violet 500 SE
FAB8276MFV500
mFluor Violet 610 SE
FAB8276MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB8276
Carrier Free
MAB8276
Carrier Free
MAB8276-SP
Carrier Free
FAB8276T-100UG
Carrier Free
FAB8276S-100UG
Carrier Free
FAB8276R-100UG
Carrier Free
FAB8276N-100UG
Carrier Free
FAB8276G-100UG
Carrier Free
FAB8276V-100UG
Carrier Free
FAB8276U-100UG
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Dopamine D1R/DRD1 Antibody (887438) [CoraFluor™ 1] Summary

Description
CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
Immunogen
NS0 mouse myeloma cell line transfected with human Dopamine D1 R/DRD1
Met1-Thr446
Accession # P21728
Specificity
Stains human Dopamine D1 R/DRD1 transfected cells but not irrelevant transfectants in flow cytometry.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
DRD1
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Immunohistochemistry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
No Preservative
Purity
Protein A or G purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for Dopamine D1R/DRD1 Antibody (887438) [CoraFluor™ 1]

  • D(1A) dopamine receptor
  • D1DR
  • DADR
  • Dopamine D1 R
  • Dopamine D1 receptor
  • Dopamine D1R
  • dopamine receptor D1
  • DRD1
  • DRD1A

Background

The members of the G protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin, and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. Beta-adrenergic receptor bound to adrenaline activates adenylyl cyclase, while alpha 2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. The dopamine receptors are divided into two classes; D1 and D2, which differ in their functional characteristics. D1 receptors stimulate adenylyl cyclase, while D2 receptors inhibit adenylyl cyclase activity. Five different subtypes of dopamine receptor have been described to date. D1DR and D5DR belong to the D1 subclass, while D2DR, D3DR and D4DR belong to the D2 subclass of dopamine receptors.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol DRD1