Dopamine D1R/DRD1 Products

Description

The members of the G protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin, and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. Beta-adrenergic receptor bound to adrenaline activates adenylyl cyclase, while alpha 2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. The dopamine receptors are divided into two classes; D1 and D2, which differ in their functional characteristics. D1 receptors stimulate adenylyl cyclase, while D2 receptors inhibit adenylyl cyclase activity. Five different subtypes of dopamine receptor have been described to date. D1DR and D5DR belong to the D1 subclass, while D2DR, D3DR and D4DR belong to the D2 subclass of dopamine receptors.

Bioinformatics

Entrez	13488 Mouse 1812 Human 24316 Rat
Uniprot	NP_000785.1 Human P18901 Rat P21728 Human
Product By Gene ID	1812
Alternate Names	D(1A) dopamine receptor D1DR DADR Dopamine D1 receptor dopamine receptor D1 DRD1A

Research Areas for Dopamine D1R/DRD1

Find related products by research area and learn more about each of the different research areas below.

GPCR
Neuroscience
Neurotransmission