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DARC Antibody (358307) [Phycoerythrin]

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Human red blood cells were stained with Mouse Anti-Human DARC PE-conjugated Monoclonal Antibody (Catalog # FAB4139P, filled histogram) or isotype control antibody (Catalog # IC003P, open histogram). View our protocol for Staining Membrane-associated Proteins.
Human red blood cells were stained with Mouse Anti-Human DARC PE-conjugated Monoclonal Antibody (Catalog # FAB4139P, filled histogram) or isotype control antibody (Catalog # IC003P, open histogram). View our protocol ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
358307
Clonality
Monoclonal
Host
Mouse
Conjugate
Phycoerythrin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB4139U-100UG
Alexa Fluor 405
FAB4139V-100UG
Alexa Fluor 488
FAB4139G-100UG
Alexa Fluor 532
FAB4139X
Alexa Fluor 594
FAB4139T-100UG
Alexa Fluor 647
FAB4139R-100UG
Alexa Fluor 700
FAB4139N-100UG
Alexa Fluor 750
FAB4139S-100UG
Allophycocyanin
FAB4139A
Allophycocyanin/Cy7
FAB4139APCCY7
Biotin
FAB4139B
CoraFluor 1
FAB4139CL1
DyLight 350
FAB4139D
DyLight 405
FAB4139E
DyLight 488
FAB4139K
DyLight 550
FAB4139L
DyLight 594
FAB4139M
DyLight 650
FAB4139W
DyLight 680
FAB4139Y
DyLight 755
FAB4139Z
HRP
FAB4139H
Janelia Fluor 525
FAB4139JF525
Janelia Fluor 549
FAB4139I
Janelia Fluor 585
FAB4139JF585
Janelia Fluor 635
FAB4139JF635
Janelia Fluor 646
FAB4139J
Janelia Fluor 669
FAB4139JF669
PE/Atto594
FAB4139PEATT594
PE/Cy5.5
FAB4139PECY55
PE/Cy7
FAB4139PECY7
Unconjugated
MAB4139
mFluor Violet 450 SE
FAB4139MFV450
mFluor Violet 500 SE
FAB4139MFV500
mFluor Violet 610 SE
FAB4139MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB4139
Carrier Free
MAB4139
Carrier Free
FAB4139A
Carrier Free
MAB4139-SP
Carrier Free
FAB4139V-100UG
Carrier Free
FAB4139U-100UG
Carrier Free
FAB4139T-100UG
Carrier Free
FAB4139S-100UG
Carrier Free
FAB4139R-100UG
Carrier Free
FAB4139N-100UG
Carrier Free
FAB4139G-100UG
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DARC Antibody (358307) [Phycoerythrin] Summary

Immunogen
HEK293 human embryonic kidney cell line transfected with human DARC
Met1-Ser336
Accession # Q16570
Specificity
Detects human DARC. Stains human DARC transfected cells but not irrelevant transfectants.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
DARC
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells
Publications
Read Publications using
FAB4139P in the following applications:

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for DARC Antibody (358307) [Phycoerythrin]

  • ACKR1
  • CCBP1
  • CD234 antigen
  • CD234
  • DARC
  • Dfy
  • Duffy Antigen
  • Duffy antigen/chemokine receptor
  • Duffy blood group antigen
  • Duffy blood group, chemokine receptor
  • Fy Antigen
  • Fy glycoprotein
  • FYDuffy blood group
  • Glycoprotein D
  • GPD
  • GPDWBCQ1
  • GpFy
  • Plasmodium vivax receptor

Background

Duffy Antigen Receptor for Chemokines (DARC), also known as Fy glycoprotein and CD234, is a 7TM non-signaling chemokine receptor that is expressed on venular endothelial cells and erythrocytes. DARC binds and mediates the internalization of several inflammatory CC and CXC chemokines. It transports chemokines to the lumenal face of venular endothelium to promote the extravasation of leukocytes to sites of inflammation. DARC polymorphisms are important in blood transfusion compatibility and determine the susceptibility of erythrocytes to Plasmodium vivax infection. Human DARC shares 60% amino acid sequence identity with mouse DARC.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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DARC Antibody
(358307) [Phycoerythr
FAB4139P
DARC Antibody (358307) [Phycoerythrin]
Species: Hu
Applications: Flow

Publications for DARC Antibody (FAB4139P)(2)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: Flow Cytometry.


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Flow Cytometry
(1)
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Bioinformatics

Gene Symbol DARC
Uniprot