Reactivity | HuSpecies Glossary |
Applications | WB, ELISA, Flow, IHC, IP |
Clone | CS9 |
Clonality | Monoclonal |
Host | Mouse |
Conjugate | PE/Cy5.5 |
Immunogen | Cytochrome B245 solubilised in octyl-beta-gluycopyranoside |
Specificity | This antibody recognises the light chain of cytochrome B245, also known as p22phox, a subunit of the nicotinamide adenine dinucleotide phosphate-oxidase (NADPH oxidase). NADPH oxidase is a membrane-bound enzyme complex in neutrophils that produces the superoxide anion (O2-) by transferring single electrons from NADPH inside the cell across the membrane and coupling them to molecular oxygen. Superoxide is used for the destruction of pathogens. Individuals with defects in NADPH oxidase suffer from chronic granulomatous disease, characterised by severe recurrent infections. |
Isotype | IgG1 |
Clonality | Monoclonal |
Host | Mouse |
Gene | CYBA |
Purity | Protein G purified |
Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
Dilutions |
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Application Notes | Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions. |
Storage | Store at 4C in the dark. Do not freeze. |
Buffer | PBS |
Preservative | 0.05% Sodium Azide |
Purity | Protein G purified |
Secondary Antibodies |
Isotype Controls |
Research Areas for Cytochrome b245 alpha Antibody (NBP1-40974PECY55)Find related products by research area.
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Gene Symbol | CYBA |