CRTH-2/GPR44 Antibody - BSA Free Summary
Description |
Product can be stored undiluted at 4C for up to 1 month. |
Immunogen |
Synthetic 20 amino acid peptide from C-terminal cytoplasmic domain of human CRTH-2/GPR44. |
Epitope |
C-Terminus |
Specificity |
Human CRTH-2/GPR44. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except KCNN2 (50%). |
Predicted Species |
Primate (100%). Backed by our 100% Guarantee. |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Rabbit |
Gene |
PTGDR2 |
Purity |
Immunogen affinity purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- ELISA
- Immunohistochemistry 15 ug/ml
- Immunohistochemistry-Paraffin 15 ug/ml
|
Application Notes |
. |
Reactivity Notes
Predicted cross-reactivity based on sequence identity: Gorilla (100%), Porcine (85%), Elephant (80%).
Packaging, Storage & Formulations
Storage |
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles. |
Buffer |
PBS |
Preservative |
0.1% Sodium Azide |
Concentration |
1.0 mg/ml |
Purity |
Immunogen affinity purified |
Alternate Names for CRTH-2/GPR44 Antibody - BSA Free
Background
GPR44, also called CRTH2, is a Prostanoid Receptor that binds prostaglandin D2. PGD2 signals through CRTH2 to induce Th2, eosinophil, and basophil chemotaxis in a G-alpha(i) dependent manner. CRTH2 may play a role in mast cell-mediated immune responses such as those involved in allergic reactions. This receptor is upregulated in activated T helper-2 (Th2) cells, peripheral blood basophils, and eosinophils, but not in Th1 lineage cells. It may be a useful marker for Th2 and Tc2 cells.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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FAQs for CRTH-2/GPR44 Antibody (NBP1-02355) (0)
Secondary Antibodies
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