Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS and NaCl with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for CRTH-2/GPR44 Antibody (301108)
CD294 antigen
CD294
Chemoattractant receptor-homologous molecule expressed on Th2 cells
CRTH2
CRTH-2
CRTH2chemoattractant receptor homologous molecule expressed on T helper type 2 cells
DL1R
DP2
G protein-coupled receptor 44
GPR44
PGD2R
PTGDR2
putative G-protein coupled receptor 44
Background
CRTH-2, also known as GPR44, is a 7TM G protein-coupled receptor that is
expressed by activated Th2 cells and eosinophils. CRTH-2 binds
Prostaglandin D2 and induces chemotaxis of these cells in allergic and
inflammatory immune responses. Human and mouse CRTH-2 share 78% amino
acid sequence identity.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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